Articles

Association between apolipoprotein gene polymorphisms and hyperlipidemia: a meta-analysis

Hyperlipidemia plays an important role in the etiology of cardio-cerebrovascular disease. Over recent years, a number of studies have explored the impact of apolipoprotein genetic polymorphisms in hyperlipidem...

Authors: Xiao-Ning Zhao, Quan Sun, You-Qin Cao, Xiao Ran and Yu Cao

Long-term dynamic compression enhancement TGF-β3-induced chondrogenesis in bovine stem cells: a gene expression analysis

Bioengineering has demonstrated the potential of utilising mesenchymal stem cells (MSCs), growth factors, and mechanical stimuli to treat cartilage defects. However, the underlying genes and pathways are large...

Authors: Jishizhan Chen, Lidan Chen, Jia Hua and Wenhui Song

Cloning and expression analysis of GATA1 gene in Carassius auratus red var

GATA1 is a key transcription factor in the GATA family, and promotes the differentiation and maturation of red blood cell, which is essential for normal hematopoiesis.

Authors: Yusu Tian, Yuandong Sun, Mi Ou, Xiaojuan Cui, Dinggang Zhou and Wen’an Che

Enhanced tolerance to drought stress resulting from Caragana korshinskii CkWRKY33 in transgenic Arabidopsis thaliana

It is well known that WRKY transcription factors play important roles in plant growth and development, defense regulation and stress responses.

Authors: Zhen Li, Fengping Liang, Tianbao Zhang, Na Fu, Xinwu Pei and Yan Long

Genome-wide association studies of plant architecture-related traits and 100-seed weight in soybean landraces

Plant architecture-related traits (e.g., plant height (PH), number of nodes on main stem (NN), branch number (BN) and stem diameter (DI)) and 100-seed weight (100-SW) are important agronomic traits and are clo...

Authors: Xiaoli Zhang, Wentao Ding, Dong Xue, Xiangnan Li, Yang Zhou, Jiacheng Shen, Jianying Feng, Na Guo, Lijuan Qiu, Han Xing and Jinming Zhao

Pineal gland transcriptomic profiling reveals the differential regulation of lncRNA and mRNA related to prolificacy in STH sheep with two FecB genotypes

Long noncoding RNA (lncRNA) has been identified as important regulator in hypothalamic-pituitary-ovarian axis associated with sheep prolificacy. However, little is known of their expression pattern and potenti...

Authors: Chunyan Li, Xiaoyun He, Zijun Zhang, Chunhuan Ren and Mingxing Chu

A simple method to estimate the in-house limit of detection for genetic mutations with low allele frequencies in whole-exome sequencing analysis by next-generation sequencing

Next-generation sequencing (NGS) has profoundly changed the approach to genetic/genomic research. Particularly, the clinical utility of NGS in detecting mutations associated with disease risk has contributed t...

Authors: Takumi Miura, Satoshi Yasuda and Yoji Sato

Genetic diversity analysis of brown marmorated stink bug, Halyomorpha halys based on mitochondrial COI and COII haplotypes

In the past decade, the brown marmorated stink bug (BMSB), Halyomorpha halys (Hemiptera: Pentatomidae) has caused extensive damage to global agriculture. As a high-risk pest for many countries, including New Zeal...

Authors: Juncong Yan, Chandan Pal, Diane Anderson, Gábor Vétek, Péter Farkas, Allan Burne, Qing-Hai Fan, Jinping Zhang, Disna N. Gunawardana, Rebijith Kayattukandy Balan, Sherly George and Dongmei Li

Comparative transcriptome analysis reveals novel insights into transcriptional responses to phosphorus starvation in oil palm (Elaeis guineensis) root

Phosphorus (P), in its orthophosphate form (Pi) is an essential macronutrient for oil palm early growth development in which Pi deficiency could later on be reflected in lower biomass production. Application o...

Authors: Sze-Ling Kong, Siti Nor Akmar Abdullah, Chai-Ling Ho, Mohamed Hanafi bin Musa and Wan-Chin Yeap

Correction to: Analyzing a putative enhancer of optic disc morphology

An amendment to this paper has been published and can be accessed via the original article.

Authors: Vladimir N. Babenko, Roman O. Babenko and Yuriy N. Orlov

The influence of QTL allelic diversity on QTL detection in multi-parent populations: a simulation study in sugar beet

Multi-parent populations (MPPs) are important resources for studying plant genetic architecture and detecting quantitative trait loci (QTLs). In MPPs, the QTL effects can show various levels of allelic diversi...

Authors: Vincent Garin, Valentin Wimmer, Dietrich Borchardt, Marcos Malosetti and Fred van Eeuwijk

Morphological characterization and genetic diversity analysis of Tunisian durum wheat (Triticum turgidum var. durum) accessions

Tunisia is considered a secondary center of diversification of durum wheat and has a large number of abandoned old local landraces. An accurate investigation and characterization of the morphological and genet...

Authors: Maroua Ouaja, Bochra A. Bahri, Lamia Aouini, Sahbi Ferjaoui, Maher Medini, Thierry C. Marcel and Sonia Hamza

Whole-transcriptome analysis of differentially expressed genes in the mutant and normal capitula of Chrysanthemum morifolium

Chrysanthemum morifolium is one of the most economically important and popular floricultural crops in the family Asteraceae. Chrysanthemum flowers vary considerably in terms of colors and shapes. However, the mol...

Authors: Hua Liu, Chang Luo, Dongliang Chen, Yaqin Wang, Shuang Guo, Xiaoxi Chen, Jingyi Bai, Mingyuan Li, Xinlei Huang, Xi Cheng and Conglin Huang

Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat

Lesion mimics (LMs) are disease-like symptoms that occur randomly on plant green leaves in the absence of pathogens. A previous study showed that LMs are related to enhanced resistance to a broad spectrum of d...

Authors: Rong Liu, Jing Lu, Shigang Zheng, Mei Du, Chihong Zhang, Minxiu Wang, Yunfang Li, Jiayi Xing, Yu Wu and Lei Zhang

Targeting the autosomal Ceratitis capitata transformer gene using Cas9 or dCas9 to masculinize XX individuals without inducing mutations

Females of the Mediterranean fruit fly Ceratitis capitata (Medfly) are major agricultural pests, as they lay eggs into the fruit crops of hundreds of plant species. In Medfly, female sex determination is based on...

Authors: Pasquale Primo, Angela Meccariello, Maria Grazia Inghilterra, Andrea Gravina, Giuseppe Del Corsano, Gennaro Volpe, Germano Sollazzo, Serena Aceto, Mark D. Robinson, Marco Salvemini and Giuseppe Saccone

Geographic distribution of sex chromosome polymorphism in Anastrepha fraterculus sp. 1 from Argentina

Anastrepha fraterculus is recognized as a quarantine pest in several American countries. This fruit fly species is native to the American continent and distributed throughout tropical and subtropical regions. It ...

Authors: María Cecilia Giardini, Mariela Nieves, Alejandra Carla Scannapieco, Claudia Alejandra Conte, Fabián Horacio Milla, María Elena Schapovaloff, Maria Soledad Frissolo, María Isabel Remis, Jorge Luis Cladera and Silvia Beatriz Lanzavecchia

Joint FAO/IAEA coordinated research project on “comparing rearing efficiency and competitiveness of sterile male strains produced by genetic, transgenic or symbiont-based technologies”

Authors: Kostas Bourtzis, Carlos Cáceres and Marc F. Schetelig

Identification and characterization of four Drosophila suzukii cellularization genes and their promoters

The spotted-wing Drosophila (Drosophila suzukii) is a widespread invasive pest that causes severe economic damage to fruit crops. The early development of D. suzukii is similar to that of other Drosophilids, but ...

Authors: Ying Yan, Syeda A. Jaffri, Jonas Schwirz, Carl Stein and Marc F. Schetelig

An early female lethal system of the New World screwworm, Cochliomyia hominivorax, for biotechnology-enhanced SIT

The New World Screwworm fly (NWS), Cochliomyia hominivorax, is an ectoparasite of warm-blooded animals and a major pest of livestock in parts of South America and the Caribbean where it remains endemic. In North ...

Authors: Carolina Concha, Ying Yan, Alex Arp, Evelin Quilarque, Agustin Sagel, Adalberto Pérez de León, W. Owen McMillan, Steven Skoda and Maxwell J. Scott

Irradiation induced inversions suppress recombination between the M locus and morphological markers in Aedes aegypti

Aedes aegypti is the primary vector of arthropod-borne viruses and one of the most widespread and invasive mosquito species. Due to the lack of efficient specific drugs or vaccination strategies, vector populatio...

Authors: Antonios A. Augustinos, Muhammad Misbah-ul-Haq, Danilo O. Carvalho, Lucia Duran de la Fuente, Panagiota Koskinioti and Kostas Bourtzis

Building a transgenic sexing strain for genetic control of the Australian sheep blow fly Lucilia cuprina using two lethal effectors

The sterile insect technique (SIT) has been successfully used in many pest management programs worldwide. Some SIT programs release both sexes due to the lack of genetic sexing strains or efficient sex separat...

Authors: Ying Yan and Maxwell J. Scott

Anosmic flies: what Orco silencing does to olive fruit flies

The olive fruit fly (Bactrocera oleae) is the most destructive pest of the olive cultivation worldwide causing significant production losses and olive fruit impoverishment, as its larvae feed exclusively on the o...

Authors: Konstantina T. Tsoumani, Alexandros Belavilas-Trovas, Maria-Eleni Gregoriou and Kostas D. Mathiopoulos

Improvement on the genetic engineering of an invasive agricultural pest insect, the cherry vinegar fly, Drosophila suzukii

The invasive fly Drosophila suzukii has become an established fruit pest in Europe, the USA, and South America with no effective and safe pest management. Genetic engineering enables the development of transgene-...

Authors: Hassan M. M. Ahmed, Fabienne Heese and Ernst A. Wimmer

Comparative genomics of Klebsiella michiganensis BD177 and related members of Klebsiella sp. reveal the symbiotic relationship with Bactrocera dorsalis

Bactrocera dorsalis is a destructive polyphagous and highly invasive insect pest of tropical and subtropical species of fruit and vegetable crops. The sterile insect technique (SIT) has been used for decades to c...

Authors: Zhaohui Cai, Qiongyu Guo, Zhichao Yao, Wenping Zheng, Junfei Xie, Shuai Bai and Hongyu Zhang

The hAT-family transposable element, hopper, from Bactrocera dorsalis is a functional vector for insect germline transformation

The hopper hAT-family transposable element isolated from the Oriental fruit fly, Bactrocera dorsalis, is distantly related to both the Drosophila hobo element and the Activator element from maize. The original 31...

Authors: Alfred M. Handler and Marc F. Schetelig

Transcriptome analysis of Anastrepha fraterculus sp. 1 males, females, and embryos: insights into development, courtship, and reproduction

Anastrepha fraterculus sp. 1 is considered a quarantine pest in several American countries. Since chemical control applied in an integrated pest management program is the only strategy utilized against this pest,...

Authors: Alejandra Carla Scannapieco, Claudia Alejandra Conte, Máximo Rivarola, Juan Pedro Wulff, Irina Muntaabski, Andrés Ribone, Fabián Milla, Jorge Luis Cladera and Silvia Beatriz Lanzavecchia

Climate stress resistance in male Queensland fruit fly varies among populations of diverse geographic origins and changes during domestication

The highly polyphagous Queensland fruit fly (Bactrocera tryoni Froggatt) expanded its range substantially during the twentieth century and is now the most economically important insect pest of Australian horticul...

Authors: Ángel-David Popa-Báez, Siu Fai Lee, Heng Lin Yeap, Shirleen S. Prasad, Michele Schiffer, Roslyn G. Mourant, Cynthia Castro-Vargas, Owain R. Edwards, Phillip W. Taylor and John G. Oakeshott

Development and characterization of a pupal-colour based genetic sexing strain of Anastrepha fraterculus sp. 1 (Diptera: Tephritidae)

Area-wide integrated pest management programs (AW-IPM) incorporating sterile insect technique (SIT) have been successful in suppressing populations of different fruit fly species during the last six decades. I...

Authors: José S. Meza, Kostas Bourtzis, Antigone Zacharopoulou, Angeliki Gariou-Papalexiou and Carlos Cáceres

Separating two tightly linked species-defining phenotypes in Bactrocera with hybrid recombinant analysis

Bactrocera tryoni and Bactrocera neohumeralis mate asynchronously; the former mates exclusively around dusk while the latter mates during the day. The two species also differ in the colour of the post-pronotal lo...

Authors: Heng Lin Yeap, Siu Fai Lee, Freya Robinson, Roslyn G. Mourant, John A. Sved, Marianne Frommer, Alexie Papanicolaou, Owain R. Edwards and John G. Oakeshott

Genetic stability, genetic variation, and fitness performance of the genetic sexing Salaya1 strain for Bactrocera dorsalis, under long-term mass rearing conditions

A genetic sexing strain (GSS) is an essential component for pest control using the sterile insect technique (SIT). A GSS is developed using a combination of Y-autosome translocation and a selectable marker suc...

Authors: Nidchaya Aketarawong, Siriwan Isasawin, Kamoltip Laohakieat and Sujinda Thanaphum

Genetic structure and symbiotic profile of worldwide natural populations of the Mediterranean fruit fly, Ceratitis capitata

The Mediterranean fruit fly, Ceratitis capitata, is a cosmopolitan agricultural pest of worldwide economic importance and a model for the development of the Sterile Insect Technique (SIT) for fruit flies of the T...

Authors: Katerina Nikolouli, Antonios A. Augustinos, Panagiota Stathopoulou, Elias Asimakis, Anastasios Mintzas, Kostas Bourtzis and George Tsiamis

Precise single base substitution in the shibire gene by CRISPR/Cas9-mediated homology directed repair in Bactrocera tryoni

Pest eradication using the Sterile Insect Technique (SIT) involves high-density releases of sterilized males that mate with wild females and ultimately suppress the population. Sterilized females are not requi...

Authors: Amanda Choo, Elisabeth Fung, Isabel Y. Chen, Robert Saint, Peter Crisp and Simon W. Baxter

Transcribed sex-specific markers on the Y chromosome of the oriental fruit fly, Bactrocera dorsalis

The Oriental fruit fly, Bactrocera dorsalis, is a highly polyphagous invasive species with a high reproductive potential. In many tropical and subtropical parts of the world it ranks as one of the major pests of ...

Authors: Davide Carraretto, Nidchaya Aketarawong, Alessandro Di Cosimo, Mosè Manni, Francesca Scolari, Federica Valerio, Anna R. Malacrida, Ludvik M. Gomulski and Giuliano Gasperi

Targeted generation of polyploids in Hydrangea macrophylla through cross-based breeding

Up to now, diploid and triploid cultivars were reported for the ornamental crop Hydrangea macrophylla. Especially, the origin of triploids and their crossing behaviors are unknown, but the underlying mechanisms a...

Authors: Conny Tränkner, Kristina Günther, Peter Sahr, Frauke Engel and Annette Hohe

Transferability, development of simple sequence repeat (SSR) markers and application to the analysis of genetic diversity and population structure of the African fan palm (Borassus aethiopum Mart.) in Benin

In Sub-Saharan Africa, Borassus aethiopum Mart. (African fan palm) is an important non-timber forest product-providing palm that faces multiple anthropogenic threats to its genetic diversity. However, this specie...

Authors: Mariano Joly Kpatènon, Kolawolé Valère Salako, Sylvain Santoni, Leila Zekraoui, Muriel Latreille, Christine Tollon-Cordet, Cédric Mariac, Estelle Jaligot, Thierry Beulé and Kifouli Adéoti

Improving the accuracy of genomic evaluation for linear body measurement traits using single-step genomic best linear unbiased prediction in Hanwoo beef cattle

Recently, there has been a growing interest in the genetic improvement of body measurement traits in farm animals. They are widely used as predictors of performance, longevity, and production traits, and it is...

Authors: Masoumeh Naserkheil, Deuk Hwan Lee and Hossein Mehrban

Genetic analysis of rice seedling traits related to machine transplanting under different seeding densities

Due to the diversity of rice varieties and cropping systems in China, the limitation of seeding density and seedling quality makes it hard to improve machine-transplanted efficiency. Previous studies have show...

Authors: Dan Zhu, Yuping Zhang, Jing Xiang, Yaliang Wang, Defeng Zhu, Yikai Zhang and Huizhe Chen

Identifying rare variants for quantitative traits in extreme samples of population via Kullback-Leibler distance

The rapid development of sequencing technology and simultaneously the availability of large quantities of sequence data has facilitated the identification of rare variant associated with quantitative traits. H...

Authors: Yang Xiang, Xinrong Xiang and Yumei Li

Genome-wide association studies for methane emission and ruminal volatile fatty acids using Holstein cattle sequence data

Methane emission by ruminants has contributed considerably to the global warming and understanding the genomic architecture of methane production may help livestock producers to reduce the methane emission fro...

Authors: Ali Jalil Sarghale, Mohammad Moradi Shahrebabak, Hossein Moradi Shahrebabak, Ardeshir Nejati Javaremi, Mahdi Saatchi, Majid Khansefid and Younes Miar

A genome-wide scan study identifies a single nucleotide substitution in MC1R gene associated with white coat colour in fallow deer (Dama dama)

The coat colour of fallow deer is highly variable and even white animals can regularly be observed in game farming and in the wild. Affected animals do not show complete albinism but rather some residual pigme...

Authors: Gerald Reiner, Tim Weber, Florian Nietfeld, Dominik Fischer, Christine Wurmser, Ruedi Fries and Hermann Willems

Functional identification of PsMYB57 involved in anthocyanin regulation of tree peony

R2R3 myeloblastosis (MYB) genes are widely distributed in plants and comprise one of the largest transcription factor gene families. They play important roles in the regulatory networks controlling development, m...

Authors: Yanzhao Zhang, Shuzhen Xu, Yanwei Cheng, Jing Wang, Xiangxiang Wang, Runxiao Liu and Jianming Han

Development of supermale and all-male Atlantic salmon to research the vgll3 allele - puberty link

Farmed Atlantic salmon are one of the most economically significant global aquaculture products. Early sexual maturation of farmed males represents a significant challenge to this industry and has been linked ...

Authors: Per Gunnar Fjelldal, Tom J. Hansen, Anna Wargelius, Fernando Ayllon, Kevin A. Glover, Rüdiger W. Schulz and Thomas W. K. Fraser

Comparative transcriptome analysis revealed resistance differences of Cavendish bananas to Fusarium oxysporum f.sp. cubense race1 and race4

Banana Fusarium wilt is a devastating disease of bananas caused by Fusarium oxysporum f. sp. cubense (Foc) and is a serious threat to the global banana industry. Knowledge of the pathogenic molecular mechanism an...

Authors: Honghong Dong, Yiting Ye, Yongyi Guo and Huaping Li

Functional analysis of bovine interleukin-10 receptor alpha in response to Mycobacterium avium subsp. paratuberculosis lysate using CRISPR/Cas9

The interleukin-10 receptor alpha (IL10RA) gene codes for the alpha chain of the IL-10 receptor which binds the cytokine IL-10. IL-10 is an anti-inflammatory cytokine with immunoregulatory function during the pat...

Authors: Sanjay Mallikarjunappa, Umesh K. Shandilya, Ankita Sharma, Kristen Lamers, Nathalie Bissonnette, Niel A. Karrow and Kieran G. Meade

The story of the lost twins: decoding the genetic identities of the Kumhar and Kurcha populations from the Indian subcontinent

The population structure of the Indian subcontinent is a tapestry of extraordinary diversity characterized by the amalgamation of autochthonous and immigrant ancestries and rigid enforcement of sociocultural s...

Authors: Ranajit Das, Vladimir A. Ivanisenko, Anastasia A. Anashkina and Priyanka Upadhyai

Studying polymorphic variants of the NAT2 gene (NAT2*5 and NAT2*7) in Nenets populations of Northern Siberia

N-acetyltransferase 2 plays a crucial role in the metabolism of a wide range of xenobiotics, including many drugs, carcinogens, and other chemicals in the human environment. The article presents for the first ...

Authors: Roza Pavlovna Tiis, Ludmila Pavlovna Osipova, Daria Veniaminovna Lichman, Elena Nikolaevna Voronina and Maxim Leonidovich Filipenko

Genetics research at the "Centenary of human population genetics" conference and SBB-2019

Authors: Tatiana V. Tatarinova, Ludmila E. Tabikhanova, Gilda Eslami, Haihua Bai and Yuriy L. Orlov

Molecular and cytological analysis of widely-used Gal4 driver lines for Drosophila neurobiology

The Drosophila central nervous system (CNS) is a convenient model system for the study of the molecular mechanisms of conserved neurobiological processes. The manipulation of gene activity in specific cell types ...

Authors: Anna A. Ogienko, Evgeniya N. Andreyeva, Evgeniya S. Omelina, Anastasiya L. Oshchepkova and Alexey V. Pindyurin

The medieval Mongolian roots of Y-chromosomal lineages from South Kazakhstan

The majority of the Kazakhs from South Kazakhstan belongs to the 12 clans of the Senior Zhuz. According to traditional genealogy, nine of these clans have a common ancestor and constitute the Uissun tribe. The...

Authors: Maxat Zhabagin, Zhaxylyk Sabitov, Pavel Tarlykov, Inkar Tazhigulova, Zukhra Junissova, Dauren Yerezhepov, Rakhmetolla Akilzhanov, Elena Zholdybayeva, Lan-Hai Wei, Ainur Akilzhanova, Oleg Balanovsky and Elena Balanovska

Genotypes diversity of env gene of Bovine leukemia virus in Western Siberia

This study describes the biodiversity and properties of Bovine leukemia virus in Western Siberia. This paper explores the effect of different genotypes of the env gene of the cattle leukemia virus on hematologica...

Authors: Natalia Blazhko, Sultan Vyshegurov, Alexander Donchenko, Kirill Shatokhin, Valeria Ryabinina, Kirill Plotnikov, Alevtina Khodakova and Sergey Pashkovskiy