LaRoche SM, Helmers SL: The new antiepileptic drugs: clinical applications. Jama. 2004, 291 (5): 615-620. 10.1001/jama.291.5.615.
Article
CAS
PubMed
Google Scholar
Sofuoglu M, Kosten TR: Novel approaches to the treatment of cocaine addiction. CNS Drugs. 2005, 19 (1): 13-25. 10.2165/00023210-200519010-00002.
Article
CAS
PubMed
Google Scholar
Thorisson GA, Smith AV, Krishnan L, Stein LD: The International HapMap Project Web site. Genome Res. 2005, 15 (11): 1592-1593. 10.1101/gr.4413105.
Article
PubMed Central
CAS
PubMed
Google Scholar
Fink-Jensen A, Suzdak PD, Swedberg MD, Judge ME, Hansen L, Nielsen PG: The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats. Eur J Pharmacol. 1992, 220 (2-3): 197-201. 10.1016/0014-2999(92)90748-S.
Article
CAS
PubMed
Google Scholar
Rosenthal M: Tiagabine for the treatment of generalized anxiety disorder: a randomized, open-label, clinical trial with paroxetine as a positive control. J Clin Psychiatry. 2003, 64 (10): 1245-1249.
Article
CAS
PubMed
Google Scholar
Mathias S, Wetter TC, Steiger A, Lancel M: The GABA uptake inhibitor tiagabine promotes slow wave sleep in normal elderly subjects. Neurobiol Aging. 2001, 22 (2): 247-253. 10.1016/S0197-4580(00)00232-3.
Article
CAS
PubMed
Google Scholar
Carpenter LL, Schecter JM, Tyrka AR, Mello AF, Mello MF, Haggarty R, Price LH: Open-label tiagabine monotherapy for major depressive disorder with anxiety. J Clin Psychiatry. 2006, 67 (1): 66-71.
Article
CAS
PubMed
Google Scholar
Gonzalez G, Sevarino K, Sofuoglu M, Poling J, Oliveto A, Gonsai K, George TP, Kosten TR: Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients: results of a randomized pilot study. Addiction. 2003, 98 (11): 1625-1632. 10.1046/j.1360-0443.2003.00544.x.
Article
PubMed
Google Scholar
Sofuoglu M, Mouratidis M, Yoo S, Culligan K, Kosten T: Effects of tiagabine in combination with intravenous nicotine in overnight abstinent smokers. Psychopharmacology (Berl). 2005, 181 (3): 504-510. 10.1007/s00213-005-0010-y.
Article
CAS
Google Scholar
Chiu CS, Brickley S, Jensen K, Southwell A, McKinney S, Cull-Candy S, Mody I, Lester HA: GABA transporter deficiency causes tremor, ataxia, nervousness, and increased GABA-induced tonic conductance in cerebellum. J Neurosci. 2005, 25 (12): 3234-3245. 10.1523/JNEUROSCI.3364-04.2005.
Article
CAS
PubMed
Google Scholar
Flowers CM, Racoosin JA, Kortepeter C: Seizure activity and off-label use of tiagabine. N Engl J Med. 2006, 354 (7): 773-774. 10.1056/NEJMc055301.
Article
CAS
PubMed
Google Scholar
Kurland L, Lind L, Melhus H: Using genotyping to predict responses to anti-hypertensive treatment. Trends Pharmacol Sci. 2005, 26 (9): 443-447.
CAS
PubMed
Google Scholar
Eaves IA, Merriman TR, Barber RA, Nutland S, Tuomilehto-Wolf E, Tuomilehto J, Cucca F, Todd JA: The genetically isolated populations of Finland and sardinia may not be a panacea for linkage disequilibrium mapping of common disease genes. Nat Genet. 2000, 25 (3): 320-323. 10.1038/77091.
Article
CAS
PubMed
Google Scholar
Shifman S, Darvasi A: The value of isolated populations. Nat Genet. 2001, 28 (4): 309-310. 10.1038/91060.
Article
CAS
PubMed
Google Scholar
The Genomatix software package [http://www.genomatix.de].
Barrett JC, Fry B, Maller J, Daly MJ: Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005, 21 (2): 263-265. 10.1093/bioinformatics/bth457.
Article
CAS
PubMed
Google Scholar
de Bakker PI, Yelensky R, Pe'er I, Gabriel SB, Daly MJ, Altshuler D: Efficiency and power in genetic association studies. Nat Genet. 2005, 37 (11): 1217-1223. 10.1038/ng1669.
Article
CAS
PubMed
Google Scholar
Stephens M, Smith NJ, Donnelly P: A new statistical method for haplotype reconstruction from population data. Am J Hum Genet. 2001, 68 (4): 978-989. 10.1086/319501.
Article
PubMed Central
CAS
PubMed
Google Scholar
Stephens M, Donnelly P: A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet. 2003, 73 (5): 1162-1169. 10.1086/379378.
Article
PubMed Central
CAS
PubMed
Google Scholar
Li N, Stephens M: Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data. Genetics. 2003, 165 (4): 2213-2233.
PubMed Central
CAS
PubMed
Google Scholar
Crawford DC, Bhangale T, Li N, Hellenthal G, Rieder MJ, Nickerson DA, Stephens M: Evidence for substantial fine-scale variation in recombination rates across the human genome. Nat Genet. 2004, 36 (7): 700-706. 10.1038/ng1376.
Article
CAS
PubMed
Google Scholar
Heils A, Teufel A, Petri S, Stober G, Riederer P, Bengel D, Lesch KP: Allelic variation of human serotonin transporter gene expression. J Neurochem. 1996, 66 (6): 2621-2624.
Article
CAS
PubMed
Google Scholar
Smeraldi E, Zanardi R, Benedetti F, Di Bella D, Perez J, Catalano M: Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine. Mol Psychiatry. 1998, 3 (6): 508-511. 10.1038/sj.mp.4000425.
Article
CAS
PubMed
Google Scholar
Zanardi R, Benedetti F, Di Bella D, Catalano M, Smeraldi E: Efficacy of paroxetine in depression is influenced by a functional polymorphism within the promoter of the serotonin transporter gene. J Clin Psychopharmacol. 2000, 20 (1): 105-107. 10.1097/00004714-200002000-00021.
Article
CAS
PubMed
Google Scholar
Pollock BG, Ferrell RE, Mulsant BH, Mazumdar S, Miller M, Sweet RA, Davis S, Kirshner MA, Houck PR, Stack JA, Reynolds CF, Kupfer DJ: Allelic variation in the serotonin transporter promoter affects onset of paroxetine treatment response in late-life depression. Neuropsychopharmacology. 2000, 23 (5): 587-590. 10.1016/S0893-133X(00)00132-9.
Article
CAS
PubMed
Google Scholar
Yu YW, Tsai SJ, Chen TJ, Lin CH, Hong CJ: Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders. Mol Psychiatry. 2002, 7 (10): 1115-1119. 10.1038/sj.mp.4001141.
Article
CAS
PubMed
Google Scholar
Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H, McClay J, Mill J, Martin J, Braithwaite A, Poulton R: Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science. 2003, 301 (5631): 386-389. 10.1126/science.1083968.
Article
CAS
PubMed
Google Scholar
Kaufman J, Yang BZ, Douglas-Palumberi H, Houshyar S, Lipschitz D, Krystal JH, Gelernter J: Social supports and serotonin transporter gene moderate depression in maltreated children. Proc Natl Acad Sci U S A. 2004, 101 (49): 17316-17321. 10.1073/pnas.0404376101.
Article
PubMed Central
CAS
PubMed
Google Scholar
Feinn R, Nellissery M, Kranzler HR: Meta-analysis of the association of a functional serotonin transporter promoter polymorphism with alcohol dependence. Am J Med Genet B Neuropsychiatr Genet. 2005, 133 (1): 79-84.
Article
Google Scholar
Nickerson DA, Taylor SL, Weiss KM, Clark AG, Hutchinson RG, Stengard J, Salomaa V, Vartiainen E, Boerwinkle E, Sing CF: DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene. Nat Genet. 1998, 19 (3): 233-240. 10.1038/907.
Article
CAS
PubMed
Google Scholar
Solus JF, Arietta BJ, Harris JR, Sexton DP, Steward JQ, McMunn C, Ihrie P, Mehall JM, Edwards TL, Dawson EP: Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population. Pharmacogenomics. 2004, 5 (7): 895-931. 10.1517/14622416.5.7.895.
Article
CAS
PubMed
Google Scholar
Badagnani I, Chan W, Castro RA, Brett CM, Huang CC, Stryke D, Kawamoto M, Johns SJ, Ferrin TE, Carlson EJ, Burchard EG, Giacomini KM: Functional analysis of genetic variants in the human concentrative nucleoside transporter 3 (CNT3; SLC28A3). Pharmacogenomics J. 2005, 5 (3): 157-165. 10.1038/sj.tpj.6500303.
Article
CAS
PubMed
Google Scholar
Nielsen R: Molecular signatures of natural selection. Annu Rev Genet. 2005, 39: 197-218. 10.1146/annurev.genet.39.073003.112420.
Article
CAS
PubMed
Google Scholar
Cheong HS, Lee SO, Choi CB, Sung YK, Shin HD, Bae SC: MERTK polymorphisms associated with risk of haematological disorders among Korean SLE patients. Rheumatology (Oxford). 2007, 46 (2): 209-214. 10.1093/rheumatology/kel182.
Article
CAS
Google Scholar
Makikyro TH, Hakko HH, Timonen MJ, Lappalainen JA, Ilomaki RS, Marttunen MJ, Laksy K, Rasanen PK: Smoking and suicidality among adolescent psychiatric patients. J Adolesc Health. 2004, 34 (3): 250-253.
Article
PubMed
Google Scholar
Yang BZ, Zhao H, Kranzler HR, Gelernter J: Practical population group assignment with selected informative markers: characteristics and properties of Bayesian clustering via STRUCTURE. Genet Epidemiol. 2005, 28 (4): 302-312. 10.1002/gepi.20070.
Article
PubMed
Google Scholar
The National Center for Biotechnology Information (NCBI) [http://www.ncbi.nlm.nih.gov/].
The PRIMER3 software [http://frodo.wi.mit.edu/cgi-bin/primer3/primer3_www.cgi].
The NCBI dbSNP [http://www.ncbi.nlm.gov/SNP].
Web application SLIDER [http://genapps.uchicago.edu/index.html].
Bamshad M, Wooding SP: Signatures of natural selection in the human genome. Nat Rev Genet. 2003, 4 (2): 99-111. 10.1038/nrg999.
Article
CAS
PubMed
Google Scholar
The POWERMARKER software [http://www.powermarker.net].
Jurka J, Kapitonov VV, Pavlicek A, Klonowski P, Kohany O, Walichiewicz J: Repbase Update, a database of eukaryotic repetitive elements. Cytogenet Genome Res. 2005, 110 (1-4): 462-467. 10.1159/000084979.
Article
CAS
PubMed
Google Scholar
Web application CENSOR [http://www.girinst.org].