Fig. 3

Identification of key DEmRNAs. A: PPI network of DEmRNAs. Red and green represent up-regulated and down-regulated DEmRNAs, respectively. B: PPI network of the top 30 DEmRNAs scored by the Betweennes algorithm. The color represents the importance of the DEmRNA in the algorithm, the darker the more important. C: PPI network of the top 30 DEmRNAs scored by the Betweennes algorithm. The color represents the importance of the DEmRNA in the algorithm, the darker the more important. D: PPI network of the top 30 DEmRNAs scored by the Degree algorithm. The color represents the importance of the DEmRNA in the algorithm, the darker the more important. E: PPI network of the top 30 DEmRNAs scored by the EPC algorithm. The color represents the importance of the DEmRNA in the algorithm, the darker the more important. F: PPI network of the top 30 DEmRNAs scored by the MCC algorithm. The color represents the importance of the DEmRNA in the algorithm, the darker the more important. G: PPI network of the top 30 DEmRNAs scored by the Stress algorithm. The color represents the importance of the DEmRNA in the algorithm, the darker the more important. H: Screening of multicentric DEmRNAs; I: Correlation between key immune cells and key DEmRNAs. Orange represents DEmRNAs, blue represents immune cells, solid line represents positive correlation, and dashed line represents negative correlation