Table 1 The first five enriched GO/KEGG pathways of top ten modules identified by SNSVD on the CGP data where “P-value” denotes Benjamini-Hochberg adjusted P-value

GO:0006952˜defense response

GO:0001775˜cell activation

GO:0045321˜leukocyte activation

GO:0006955˜immune response

GO:0042110˜T cell activation

GO:0006955˜immune response

GO:0006414˜translational elongation

hsa03010:Ribosome

hsa04662:B cell receptor signaling pathway

GO:0001775˜cell activation

GO:0006414˜translational elongation

hsa03010:Ribosome

GO:0006412˜translation

GO:0042273˜ribosomal large subunit biogenesis

GO:0042254˜ribosome biogenesis

GO:0006836˜neurotransmitter transport

GO:0030182˜neuron differentiation

GO:0007269˜neurotransmitter secretion

GO:0050767˜regulation of neurogenesis

GO:0048667˜cell morphogenesis involved in neuron diff.

GO:0042110˜T cell activation

hsa04660:T cell receptor signaling pathway

GO:0045321˜leukocyte activation

GO:0001775˜cell activation

GO:0046649˜lymphocyte activation

GO:0051276˜chromosome organization

GO:0006350˜transcription

GO:0006325˜chromatin organization

GO:0045449˜regulation of transcription

GO:0008380˜RNA splicing

hsa04080:Neuroactive ligand-receptor interaction

GO:0006955˜immune response

hsa05330:Allograft rejection

hsa04940:Type I diabetes mellitus

hsa05332:Graft-versus-host disease

hsa04672:Intestinal immune network for IgA production