Skip to main content
Fig. 10 | BMC Genomic Data

Fig. 10

From: Analysis of transcriptomic data sets supports the role of IL-6 in NETosis and immunothrombosis in severe COVID-19

Fig. 10

CEACAM8 gene expression increases with COVID-19 disease severity. CEACAM8 gene expression in PBMC of healthy control (n = 6) and COVID-19 (n = 7) were extracted from published data set [14]. Group-level expression (aggregate log counts) data are shown in the box plot, with monotonic up-regulation of CEACAM8 genes from the control group, to COVID-19 cases without ARDS (NonVent) and with ARDS. CEACAM8 up-regulation is a signature of immature or developing neutrophil, a neutrophil subtype associated with COVID-19. Statistical significance of the difference in DNASE1 transcript levels was calculated using analysis of variance (Anova)

Back to article page

BMC Genomic Data

ISSN: 2730-6844

Contact us