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Fig. 1 | BMC Genetics

Fig. 1

From: MCC-SP: a powerful integration method for identification of causal pathways from genetic variants to complex disease

Fig. 1

The proportion that correctly pinpoint the top 4 pathways among 500 simulations under two criteria when the sample size is 500 and the proportion of nonlinear components is 40%.The nonlinear pattern is (a) \( \boldsymbol{\varphi} \left({\boldsymbol{x}}_{\boldsymbol{i}}\right)=\sqrt{\boldsymbol{C}-{\boldsymbol{x}}_{\boldsymbol{i}}^{\mathbf{2}}}+\boldsymbol{\varepsilon} \), (b) φ(xi) =  cos (xi) + ε, (c) mixed nonlinear pattern(6 edges having cosine and 3 edges having quadratic relationship) and (d) \( \boldsymbol{\varphi} \left({\boldsymbol{x}}_{\boldsymbol{i}}\right)={\boldsymbol{x}}_{\boldsymbol{i}}^{\mathbf{2}}+\boldsymbol{\varepsilon} \) respectively

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