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Table 9 The detected pathways with statistical significance contributing to survival time in GBM patients

From: A novel path-specific effect statistic for identifying the differential specific paths in systems epidemiology

Path list

PSE

SE

P value

SLC7A5 → mLST8 → Lipin-1

2.11046

0.995

0.017

SLC7A5 → Tel2 → CLIP-170

1.977606

0.99

0.023

SLC7A5 → Tel2 → Lipin-1

1.718378

0.8765

0.025

SLC7A5 → Tel2 → ATG1

2.595217

1.077

0.008

SLC3A2 → mLST8 → Lipin-1

3.461764

1.203

0.002

SLC3A2 → Tel2 → CLIP-170

2.021598

0.93

0.015

SLC3A2 → Tel2 → Lipin-1

1.94616

0.966

0.022

SLC3A2 → Tel2 → ATG1

2.742903

1.198

0.011

RNF152 → mLST8 → eIF4B

−2.32003

1.214

0.028

GATOR1 → Tel2 → CLIP-170

1.806073

1.01

0.037

GATOR1 → Tel2 → ATG1

1.791135

1.02

0.04

STRAD→Tel2 → CLIP-170

1.754709

1.029

0.044

IGF → R → IRS1 → PDK1 → TSC1/6 → Rheb→mLST8 → eIF4B

1.143228

0.691

0.049

IGF → IRS1 → PDK1 → mLST8 → eIF4B

1.151496

0.675

0.044