KEGG group | KEGG sub-group | Pathway | Genes | Control | Stress | ||
---|---|---|---|---|---|---|---|
gage | romer | gage | romer | ||||
Cellular Processes | Cell communication | Focal adhesion | 98 | 2D | Down | 2D | Down |
Gap junction | 39 | 2D | Down | ||||
Cell growth and death | Cell cycle – yeast | 54 | Up | Up | Up | Up | |
Transport and catabolism | Phagosome | 76 | Down | Down/Mixed | Down | Down/Mixed | |
Endocytosis | 105 | Down/2D | Down | Down/2D | Down | ||
Peroxisome | 54 | Up | Up | Up | Up | ||
Environmental Information Processing | Membrane transport | ABC transporters | 27 | Up | Mixed | ||
Signal transduction | MAPK signaling pathway | 110 | 2D | Down | 2D | Down | |
NF-kappa B signaling pathway | 64 | 2D | Down | ||||
Jak-STAT signaling pathway | 56 | 2D | Down | ||||
Calcium signaling pathway | 72 | 2D | Down | 2D | Down | ||
PI3K-Akt signaling pathway | 149 | 2D | Down/Mixed | Down/2D | Down | ||
VEGF signaling pathway | 28 | 2D | Down | ||||
Signaling molecules and interaction | Cell adhesion molecules (CAMs) | 64 | 2D | Down/Mixed | 2D | Down | |
Neuroactive ligand-receptor interaction | 112 | Down/2D | Down | ||||
Cytokine-cytokine receptor interaction | 94 | Down/2D | Down | 2D | Down | ||
Genetic Information Processing | Replication and repair | DNA replication | 33 | Up | Up | ||
Transcription | RNA polymerase | 27 | Up | Up | Up | Up | |
Spliceosome | 109 | Up | Up | ||||
Translation | Ribosome biogenesis in eukaryotes | 64 | Up | Up | Up | Up/Mixed | |
RNA transport | 111 | Up | Up | Up | Up/Mixed | ||
Ribosome | 118 | Up | Up/Mixed | Up | Up/Mixed | ||
Metabolism | Amino acid metabolism | Arginine and proline metabolism | 36 | Up | Up | ||
Carbohydrate metabolism | Amino sugar & nucleotide sugar metabolism | 35 | Up | Up/Mixed | Up | Up/Mixed | |
Galactose metabolism | 16 | Up | Up/Mixed | Up | Up/Mixed | ||
Fructose and mannose metabolism | 19 | Up | Up/Mixed | Up | Up/Mixed | ||
Glycolysis / Gluconeogenesis | 30 | Up | Up/Mixed | ||||
Lipid metabolism | Sphingolipid metabolism | 21 | Up | Up | Up | Up | |
Biosynthesis of unsaturated fatty acids | 15 | Up | Up/Mixed | Up | Up/Mixed | ||
Glycerolipid metabolism | 25 | Up | Up/Mixed | ||||
Primary bile acid biosynthesis | 12 | Up | Up/Mixed | Up | Up/Mixed | ||
Nucleotide metabolism | Pyrimidine metabolism | 73 | Up | Up/Mixed | Up | Up | |
Xenobiotics biodegradation and metabolism | Drug metabolism - cytochrome P450 | 11 | Down | Down/Mixed | Down/2D | Down/Mixed | |
Organismal Systems | Circulatory system | Vascular smooth muscle contraction | 55 | 2D | Down | Down/2D | Down |
Development | Osteoclast differentiation | 69 | 2D | Down | 2D | Down | |
Axon guidance | 52 | Down/2D | Down | ||||
Digestive system | Protein digestion and absorption | 40 | 2D | Mixed | |||
Vitamin digestion and absorption | 17 | 2D | Up/Mixed | ||||
Mineral absorption | 25 | Up | Up/Mixed | ||||
Fat digestion and absorption | 19 | Up | Up/Mixed | Up | Up/Mixed | ||
Bile secretion | 39 | Up/2D | Up/Mixed | Up/2D | Up | ||
Salivary secretion | 32 | Down/2D | Down | ||||
Endocrine system | Ovarian steroidogenesis | 22 | 2D | Down | 2D | Down | |
Thyroid hormone synthesis | 33 | 2D | Up/Mixed | ||||
PPAR signaling pathway | 42 | Up | Up | ||||
Insulin secretion | 37 | 2D | Down | ||||
Environmental adaptation | Circadian entrainment | 45 | 2D | Down | Down/2D | Down | |
Immune system | T cell receptor signaling pathway | 61 | 2D | Down | |||
Fc epsilon RI signaling pathway | 29 | 2D | Down | 2D | Down/Mixed | ||
B cell receptor signaling pathway | 39 | 2D | Down | Down/2D | Down | ||
Complement and coagulation cascades | 56 | Down | Down/Mixed | Down | Down/Mixed | ||
Hematopoietic cell lineage | 38 | Down/2D | Down/Mixed | Down | Down | ||
Chemokine signaling pathway | 88 | Down/2D | Down/Mixed | Down/2D | Down/Mixed | ||
Natural killer cell mediated cytotoxicity | 40 | Down/2D | Down/Mixed | Down/2D | Down | ||
Nervous system | Glutamatergic synapse | 50 | 2D | Down | Down/2D | Down | |
Synaptic vesicle cycle | 35 | Down | Down | ||||
Serotonergic synapse | 49 | Down | Down | Down | Down | ||
Retrograde endocannabinoid signaling | 46 | 2D | Down | ||||
Sensory system | Phototransduction | 14 | Down | Down |