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Table 5 Genetic effects of thirteen indels in eight genes on five milk production traits

From: Determination of genetic associations between indels in 11 candidate genes and milk composition traits in Chinese Holstein population

Locus Gene Gene effects MY FY FP PY PP
rs381714237 FCGR2B Additive effect(a) 66.13* 0.83 −0.0072 2.99** 0.0051
Dominant effect(d) 123.27 0.27 − 0.0618 0.47 −0.0348**
Substitution effect(α) 30.92 0.76 0.0105 2.85* 0.0150*
ss2137349053 CENPE Additive effect(a) 224.66** 5.81** −0.0174 6.32** − 0.0002
Dominant effect(d) 33.43 −1.57 −0.0246 0.98 0.0028
Substitution effect(α) 227.29** 5.69** −0.0193 6.4** 0.0001
rs385060942 CENPE Additive effect(a) −188.63** −5.66** 0.007 −5.89** −0.0042
Dominant effect(d) 34.37 −0.71 −0.0218 1.84 0.0065
Substitution effect(α) −191.51** −5.60** 0.0089 −6.05** −0.0048
ss2137349051 CENPE Additive effect(a) −209.61** − 6.16** 0.0093 − 6.25** −0.0009
Dominant effect(d) −20.82 − 2.24 −0.014 −0.44 0.0022
Substitution effect(α) −208.06** −6.00** 0.0103 −6.22** −0.0011
rs453960300 CENPE Additive effect(a) − 192.46** −5.40** 0.0105 − 5.27** 0.0015
Dominant effect(d) 13.90 −0.55 −0.0106 0.43 0.0017
Substitution effect(α) −193.46** −5.36** 0.0113 −5.31** 0.0014
rs378415122 CENPE Additive effect(a) −205.95** −6.59** 0.0069 −6.19** −0.0011
Dominant effect(d) −32.03 −1.87 −0.0068 − 0.85 0.0022
Substitution effect(α) −203.68** −6.46** 0.0073 −6.13** −0.0012
rs134985825 RETSAT Additive effect(a) 24.57 2.49 0.0156 2.74* 0.0163**
Dominant effect(d) − 235.31** −8.32** 0.0001 −6.52** 0.0036
Substitution effect(α) 29.53 2.67 0.0156 2.88* 0.0162**
rs377943075 ACSBG2 Additive effect(a) −69.28 −6.30** −0.0272 −0.35 0.0154*
Dominant effect(d) −39.32 2.48 0.0178 0.26 0.0108
Substitution effect(α) −56.34 −7.12* −0.033 −0.44 0.0118
rs136639319 TBC1D1 Additive effect(a) 47.54 −1.85 −0.0342** 0.02 −0.0127**
Dominant effect(d) 140.15 10.02 0.0346 5.74 0.0103
Substitution effect(α) 98.36 1.79 −0.0216 2.11 −0.0089
rs379188781 NLK Additive effect(a) −36.45 −3.58 −0.0057 1.16 0.0194**
Dominant effect(d) −85.74 0.43 0.0343 −2.59 −0.0039
Substitution effect(α) −55.71 −3.48 0.002 0.58 0.0185*
rs134444531 NLK Additive effect(a) 92.55 1.30 −0.0226 4.86** 0.0169*
Dominant effect(d) 67.33 3.36 0.0084 0.75 −0.0055
Substitution effect(α) 97.88 1.57 −0.0219 4.92** 0.0164*
ss2137349058 MAP3K1 Additive effect(a) −213.49** −8.92** −0.0046 −6.56** 0.0013
Dominant effect(d) −82.74 −5.08* −0.0264 −2.45 0.0043
Substitution effect(α) −208.37** −8.60** −0.0029 −6.41** 0.0011
ss2019489562 UGDH Additive effect(a) 31.00 −0.36 − 0.0032 1.63 0.0097*
Dominant effect(d) −925.95* −11.33 0.1715 −16.94 0.0462
Substitution effect(α) −42.62 −1.27 0.0104 0.28 0.0134*
  1. Note: (a), (d), (α) means Additive, Dominant and Substitution effect, respectively
  2. * means the additive, dominant or allele substitution effect of the locus indicated differ at P < 0.05 and ** means the additive, dominant or allele substitution effect of the locus indicated differ at P < 0.01
  3. MY milk yield, FY fat yield, FP fat percentage, PY protein yield, PP protein percentage