Determination of genetic associations between indels in 11 candidate genes and milk composition traits in Chinese Holstein population

Table 1 Detailed information of 24 indels of 11 genes identified in Chinese Holstein cattle

Indel	Gene	Location	GenBank no.	Position in UMD_3.1	Indel Sequence	Confirmed?
1 N ins	FCGR2B	exon7	rs381714237	chr3:7930047	G	1
3 N ins	CENPE	exon58	ss2137349053	chr6:23018080	AGA	1
3 N del	CENPE	exon68	–	chr6:23026632–23026634	TAG	3
3 N ins	CENPE	intron13	rs385060942	chr6:22983076	GTT	1
1 N ins	CENPE	intron13	ss2137349051	chr6:22983397	T	1
1 N del	CENPE	intron18	rs384082187	chr6:22989805	A	2
21 N ins	CENPE	intron24	rs377812754	chr6:22996564–22996573	ACTTAAGTATATAACCTTAAC	2
2 N del	CENPE	intron41	rs453960300	chr6:23018994–23018995	CC	1
1 N del	CENPE	intron49	rs378415122	chr6:23036105	C	1
4 N ins	CENPE	intron51	ss2137349056	chr6:23040582	ACAC	4
2 N del	RETSAT	3’UTR	rs136527375	chr11:49489416–49489417	AA	2
9 N ins	RETSAT	intron6	rs134985825	chr11:49485899	ATTCTGGGG	1
1 N ins	ACSBG2	intron7	rs377943075	chr7:19476990	G	1
2 N ins	NFKB2	5′ regulatory region	–	chr26:22891203	GG	3
1 N del	TBC1D1	intron1	rs136639319	chr6:58898979	T	1
1 N ins	NLK	intron1	rs137724510	chr19:20180649	T	2
2 N del	NLK	intron1	rs379188781	chr19:20189055–20189056	AT	1
1 N del	NLK	intron3	rs135129224	chr19:20264835	A	2
4 N del	NLK	intron3	rs134444531	chr19:20276109–20276112	AAAA	1
5 N del	MAP3K1	intron16	ss2137349058	chr20:22365627–22365631	CATTT	1
6 N del	SLC30A2	intron2	ss2137349049	chr2:127640012–127640017	TTTTTG	2
2 N ins	ANGPT1	intron1	ss2137349057	chr14:59305051	AT	2
1 N ins	UGDH	intron7	rs383327605	chr6:60236955	T	2
1 N ins	UGDH	intron2	ss2019489562	chr6:60252782	G	1

Note: ¹ indels were genotyped successfully; ² indels were failed to genotype using MALDI-TOF MS; ³ indels were not polymorphic in current population; ⁴ primers of indel were failed to design

ISSN: 2730-6844