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Table 2 Genes with the most significant differences in expression between primary tumours and metastases

From: Exome scale map of genetic alterations promoting metastasis in colorectal cancer

RefSeq ID

gene symbol

gene name

FC

adjusted p-value

NM_000567

CRP

C-reactive protein

85.0

2.36E-21

NM_021870

FGG

fibrinogen gamma chain

56.0

1.98E-12

NM_001204307

GC

GC, vitamin D binding protein

29.1

1.19E-08

NM_002216

ITIH2

inter-alpha-trypsin inhibitor heavy chain 2

26.1

1.43E-06

NM_005141

FGB

fibrinogen beta chain

25.1

4.18E-05

NM_000042

APOH

apolipoprotein H

22.2

4.18E-05

NM_002215

ITIH1

inter-alpha-trypsin inhibitor heavy chain 1

22.0

1.81E-05

NM_000607

ORM1

orosomucoid 1

16.0

8E-06

NM_004467

FGL1

fibrinogen like 1

14.2

0.003387

NM_001063

TF

transferrin

12.9

0.000902

NM_000505

F12

coagulation factor XII

12.3

0.003333

NM_145285

NKX2–3

NK2 homeobox 3

0.055

2.63E-07

NM_003480

MFAP5

microfibrillar associated protein 5

0.068

6.59E-05

NM_004950

EPYC

epiphycan

0.070

0.001189

NM_002148

HOXD10

homeobox D10

0.071

7.38E-05

NM_001170807

FHL5

four and a half LIM domains 5

0.078

4.18E-05

NM_001145311

PLIN1

perilipin 1

0.080

0.001189

NM_019849

SLC7A10

solute carrier family 7 member 10

0.080

0.00042

  1. FC - fold change (expression in metastases/expression in primary tumours)