Genetic loci for resistance to podocyte injury caused by the tensin2 gene deficiency in mice

BMC Genomic Data

Table 1 Relationship between albuminuria and genotype for genetic markers on chromosomes 2 and 10

Chromosome	Marker	Position (cM)	χ² (P)				Student-T (P)^c
Chromosome	Marker	Position (cM)	Min/Max^a	50%^b	40%^b	30%^b	Min/Max	50%	40%	30%
2	D2Mit398	61.76	0.19	0.062	0.052	0.20	0.48	0.47	0.40	0.31
2	rs214164633	65.66	0.16	0.080	0.075	0.20	0.26	0.25	0.24	0.18
2	rs234188972	70.98	0.18	0.067	0.062	0.24	0.14	0.16	0.14	0.10
2	rs247793542	75.41	0.64	0.36	0.30	0.84	0.25	0.23	0.26	0.24
2	rs228447345	81.91	0.65	0.28	0.44	1	0.42	0.45	0.49	0.49
10	D10Mit298	2.78	0.58	0.42	0.60	0.48	0.43	0.47	0.36	0.29
10	D10Mit3	16.53	0.010	0.053	0.086	0.04	0.0099	0.0084	0.012	0.013
10	D10Mit197	35	0.049	0.059	0.059	0.10	0.0078	0.011	0.012	0.014
10	rs259766385	40.66	0.0022	0.0039	0.0068	0.0065	0.00038	0.00098	0.00074	0.00061
10	rs239646663	43.64	0.0043	0.0099	0.0040	0.019	0.00053	0.00076	0.0010	0.0015
10	D10Mit233	61.58	0.054	0.092	0.042	0.079	0.14	0.17	0.20	0.15

^aThe N2 mice with urinary albumin excretion larger than 3.1 g/gCr, the minimum value in FVB-Tns2^nph mice, were defined as the FVB type (affected) and the N2 mice with urinary albumin excretion less than 0.7 g/gCr, the maximum value in B6- Tns2^nph mice, were defined as the B6 type (not affected)
^bThe upper X% and lower X% of N2 mice in urinary albumin excretion were defined as the FVB type (affected) and the B6 type (not affected), respectively
^cUrinary albumin excretion in N2 mice was compared between those with B6/FVB and FVB/FVB genotypes at the genetic markers

ISSN: 2730-6844