Detecting TF-miRNA-gene network based modules for 5hmC and 5mC brain samples: a intra- and inter-species case-study between human and rhesus

Table 6 Top ten targeter miRNAs for Rhesus monkey (that are connected with maximum number of gene-modules and that target maximum number genes from the connected modules) with information of their maximum number of targeted genes as well as gene-modules, and verified information of them

Sl. No.	MiRNAs	Number o connected gene-modules	Number of targeted genes	Name of the connected gene-modules (number of targeted genes in the modules)	Disease and Disease-verified information of miRNAs	Status of miRNAs
1	mml-miR-338-5p	2	33	Blue (6), Turquoise (27).	An auto immune disease like SIV [52]	Known
2	mml-miR-218	2	25	Blue (6), Turquoise (19).	Huntintong’s Disease [53]	Known
3	mml-miR-768-3p	2	25	Blue (9), Turquoise (16).		Unknown
4	mml-miR-495	2	24	Blue (10), Turquoise (14).	Age mediated skeletal muscle contamination [54]	Known
5	mml-miR-203	2	24	Blue (6), Turquoise (18).	Enhances Coxsackievirus B3 replication [55]	Known
6	mml-miR-561	2	24	Blue (11), Turquoise (13).		Unknown
7	mml-miR-590-3p	2	23	Blue (6), Turquoise (17).	Neuro inflammation Disorder [56]	Known
8	mml-miR-596	2	23	Blue (2), Turquoise (21).	Schizophernia [57]	Known
9	mml-miR-548p	2	22	Blue (11), Turquoise (11).	monkey hippocampus effected [58].	Known
10	mml-miR-524-5p	2	22	Blue (8), Turquoise (14).	Amyotrophic lateral sclerosis [59].	Known

ISSN: 2730-6844