Skip to main content

Table 4 Top ten targeter miRNAs for Human (that are connected with maximum number of gene-modules and that target maximum number genes from the connected modules) with information of their maximum number of targeted genes as well as gene-modules, and verified information of them

From: Detecting TF-miRNA-gene network based modules for 5hmC and 5mC brain samples: a intra- and inter-species case-study between human and rhesus

Sl. No. MiRNAs Number of connected gene-modules Number of targeted genes Name of the connected gene-modules (number of targeted genes in the modules) Disease and Disease-verified information of miRNAs Status of miRNAs
1 hsa-miR-579 4 17 Blue (2), Brown (2), Green (1), Turquoise (12). Alzheimer’s Disease [38] Known
2 hsa-miR-495 4 14 Blue (5), Brown (2), Green (1), Turquoise (6). HIV mediated dementia [39] Known
3 hsa-miR-27b-3p-3p 4 10 Blue (5), Brown (1), Green (1), Turquoise (3). Presence in high intensity for Alzheimer’s disease [74] Known
4 hsa-miR-449b-5p-5p 4 10 Blue (1), Brown (2), Green (1), Turquoise (6). Presence in low intensity in case of Alzheimer’s disease Known
5 hsa-miR-34a 4 10 Blue (1), Brown (2), Green (1), Turquoise (6). neuropsychaitric and nuerodegenrative diseases [40] Known
6 hsa-miR-34c-5p 4 10 Blue (1), Brown (2), Green (1), Turquoise (6). Bipolar disorder and Schizophenia [41] Known
7 hsa-miR-449a 4 10 Blue (1), Brown (2), Green (1), Turquoise (6). Molecular Targets for Neurodegenerative Diseases [42] Known
8 hsa-miR-607 4 9 Blue (3), Brown (3), Green (1), Turquoise (2). Neurodegenerative diseases [43] Known
9 hsa-miR-27a-3p 4 9 Blue (4), Brown (1), Green (1), Turquoise (3). Alzheimer’s Disease [75] Known
10 hsa-miR-664-3p 4 9 Blue (2), Brown (2), Green (1), Turquoise (4). Psychiatric and Neurodegenerative disease [44]. Known