|
Study
|
n
|
\(\bar \lambda \)
|
\(\bar \lambda _{10\%}\)
|
λ
′
|
λ
f;m;c′
|
\(\bar {G}\)
|
\(R^{2}_{\mathrm {t}}\)
|
|---|
|
HapMap
|
129
|
1.288 (0.074)
|
1.295 (0.051)
|
1.297
|
-
|
0.006
|
0.152
|
|
SFS1
|
129
|
1.284 (0.087)
|
1.293 (0.051)
|
1.294
|
1.295
|
0.007
|
0.153
|
|
SFS2
|
999
|
1.306 (0.050)
|
1.313 (0.020)
|
1.314
|
1.299
|
0.001
|
0.143
|
|
Sorbs
|
977
|
1.410 (0.135)
|
1.448 (0.071)
|
1.449
|
-
|
0.001
|
0.100
|
|
SFS3
|
999
|
2.006 (0.139)
|
2.022 (0.083)
|
2.021
|
2.002
|
0.002
|
0.044
|
- Variance inflation and related measures are compared between the data sets HapMap, SFS1 (synthetic family study 1), SFS2, Sorbs and SFS3 assuming \(R^{2}_{\mathrm {h}}=0.9\). Provided are the sample size n, average inflation \(\bar \lambda \) of all SNPs, average inflation \(\bar \lambda _{10\%}\) estimated for SNPs with minor allele frequencies > 10%, expected (theoretical) inflation λ
′ obtained from estimated relationships, expected inflation λ
f;m;c′ obtained from true relationships (synthetic family studies only), mean relatedness \(\bar {G}\) and heritability \(R^{2}_{\mathrm {t}}\)corresponding to inflation λt′=1.05. Standard deviations are given in parentheses
