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Fig. 4 | BMC Genetics

Fig. 4

From: Resampling-based tests for Lasso in genome-wide association studies

Fig. 4

Diagnostic plots for Lasso-PL with the alcohol consumption quantitative trait. The figure on the left shows the total number of selected SNPs for a given number of permutations (B) used in the estimator \(\bar {\lambda }_{\alpha }.\) Ideally, as the number of permutations increases, the number of selected SNPs should converge to some constant \(\left (\text {since } Var\left (\bar {\lambda }_{\alpha }\right)\mathop {\rightarrow }\limits _{B\to \infty } 0\right)\). The figure on the right shows the number of discrepant SNPs between models using B and B−1 permutations in the estimator \(\bar {\lambda }_{\alpha }\). Ideally, as B increases, the number of discrepant SNPs should converge to 0

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