Groups | Variant combinations | `Haplotypes | Control | Proband | Chi-square (p-value) | Odds Ratio (95Â % confidence interval) |
---|---|---|---|---|---|---|
Alla | rs4824562-rs56220155-rs2283728-rs2283727-rs3027441-rs6324-rs3027440 | A-A-C-C-T-C-C | 0.04 | 0 | 5.27 (0.02) | 0.13 (0.03–0.65) |
A-A-C-C-T-C-T | 0.32 | 0.49 | 12.14 (0.0005) | 2.08 (1.36–3.19) | ||
A-A-T-C-T-C-C | 0.02 | 0 | 4.02 (0.04) | 0.13 (0.02–0.96) | ||
A-A-T-C-T-C-T | 0.03 | 0 | 6.07 (0.01) | 0.13 (0.03–0.66) | ||
A-G-C-C-T-C-T | 0.03 | 0.09 | 4.06 (0.04) | 2.5 (1.04–6.03) | ||
A-G-T-A-C-T-C | 0.07 | 0.15 | 4.29 (0.038) | 2.21 (1.13–4.32) | ||
A-G-T-C-T-C-T | 0.03 | 0 | 5.04 (0.02) | 0.13 (0.02–0.78) | ||
G-A-C-C-T-C-C | 0.03 | 0 | 4.03 (0.04) | 0.13 (0.02–0.88) | ||
G-A-C-C-T-C-T | 0.08 | 0.18 | 6.26 (0.01) | 2.46 (1.33–4.58) | ||
G-A-T-C-T-C-T | 0.02 | 0 | 4.02 (0.04) | 0.13 (0.02–0.96) | ||
G-G-T-A-T-C-C | 0.02 | 0 | 4.06 (0.04) | 0.13 (0.02–0.91) | ||
G-G-T-A-T-C-T | 0.04 | 0 | 7.05 (0.008) | 0.13 (0.03–0.57) | ||
G-G-T-C-T-C-T | 0.02 | 0 | 3.01 (0.08) | 0.14 (0.01–1.3) | ||
rs2283728-rs3027440 | C-C | 0.11 | 0.02 | 9.43 (0.002) | 0.25 (0.11–0.57) | |
C-T | 0.47 | 0.77 | 32.72 (1.07e-008) | 3.6 (2.34–5.55) | ||
T-C | 0.16 | 0.16 | 0.07 (0.78) | 0.98 (0.55–1.75) | ||
T-T | 0.27 | 0.05 | 28.27 (1.05e-007) | 0.2 (0.12–0.36) | ||
Maleb | rs4824562-rs56220155-rs2283728-rs2283727-rs3027441-rs6324-rs3027440 | A-A-C-C-T-C-C | 0.05 | 0 | 6.2 (0.01) | 0.13 (0.03–0.65) |
A-A-C-C-T-C-T | 0.26 | 0.53 | 19.98 (7.85e-006) | 3.16 (1.2–5.23) | ||
A-A-T-C-T-C-C | 0.03 | 0 | 4.1 (0.04) | 0.13 (0.02–0.94) | ||
A-A-T-C-T-C-T | 0.03 | 0 | 4.1 (0.04) | 0.13 (0.02–0.94) | ||
A-G-T-A-C-T-C | 0.04 | 0.15 | 8.91 (0.003) | 3.58 (1.55–8.3) | ||
A-G-T-A-T-C-T | 0.06 | 0.008 | 5.71 (0.016) | 0.2 (0.05–0.75) | ||
A-G-T-C-T-C-T | 0.04 | 0 | 5.14 (0.02) | 0.13 (0.02–0.76) | ||
G-A-C-C-T-C-C | 0.03 | 0 | 4.1 (0.04) | 0.13 (0.02–0.94) | ||
G-A-C-C-T-C-T | 0.06 | 0.17 | 7.75 (0.005) | 3.04 (1.39–6.66) | ||
G-A-T-C-T-C-T | 0.03 | 0 | 4.1 (0.04) | 0.13 (0.02–0.94) | ||
G-G-T-A-T-C-C | 0.03 | 0 | 4.1 (0.04) | 0.13 (0.02–0.94) | ||
G-G-T-A-T-C-T | 0.02 | 0 | 3.06 (0.08) | 0.13 (0.01–1.28) | ||
G-G-T-C-T-C-T | 0.02 | 0 | 3.06 (0.08) | 0.13 (0.01–1.28) | ||
 | rs56220155-rs2283728-rs3027440 | A-C-C | 0.13 | 0.02 | 11.85 (0.0006) | 0.19 (0.07–0.49) |
A-C-T | 0.33 | 0.71 | 35.98 (1.99e-009) | 4.52 (2.76–7.42) | ||
A-T-C | 0.05 | 0 | 6.2 (0.01) | 0.13 (0.03–0.65) | ||
A-T-T | 0.1 | 0 | 12.7 (0.0004) | 0.12 (0.04–0.39) | ||
G-C-C | 0.02 | 0 | 2.03 (0.15) | 0.13 (0.008–2.14) | ||
G-C-T | 0.06 | 0.08 | 0.54 (0.46) | 1.45 (0.54–3.86) | ||
G-T-C | 0.11 | 0.16 | 1.17 (0.28) | 1.49 (0.72–3.06) | ||
G-T-T | 0.22 | 0.04 | 17.54 (2.82e-005) | 0.21 (0.1–0.43) | ||
Femalec | rs4824562-rs56220155-rs2283728-rs2283727-rs3027441-rs6324-rs3027440 | A-G-C-C-T-C-T | 0 | 0.08 | 3.69 (0.055) | 8.23 (1.13–59.77) |
G-G-T-A-T-C-T | 0.08 | 0 | 4.16 (0.04) | 0.13 (0.02–0.97) |