BMC Genomic Data

Table 1 The overall TDR, FDR and MCC of three schemes of scenario 1 with 1000 cases and 1000 controls in each scheme

From: A novel Markov Blanket-based repeated-fishing strategy for capturing phenotype-related biomarkers in big omics data

Methods	Scheme 2			Scheme 3			Scheme 4
Methods	TDR_overall	FDR	MCC	TDR_overall	FDR	MCC	TDR_overall	FDR	MCC
Bonferroni	0.65	0.00	0.80	0.33	0.01	0.57	0.14	0.10	0.35
B-H	0.71	0.03	0.82	0.38	0.03	0.61	0.18	0.10	0.40
LASSO	0.52	0.00	0.72	0.75	0.17	0.78	0.76	0.44	0.65
DASSO-MB	0.52	0.01	0.72	0.43	0.11	0.65	0.24	0.28	0.41
MBRFS	0.80	0.14	0.83	0.78	0.16	0.81	0.58	0.20	0.68

Bonferroni and B-H is the multiply correction methods after χ ² tests
TDR true discovery rate
FDR false discovery rate
MCC matthews correlation coefficience

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ISSN: 2730-6844

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