Fig. 1

Human HTR2A-AS1 (green) and HTR2A (blue) gene locus (chr13:47,370,678-47,844,384). a The current RefSeq annotation for HTR2A-AS1 includes three exons located within the third intron of HTR2A. b Splice junction analysis expands the number of exons for both HTR2A-AS1 to include 18 total exons, three of which overlap with exons at the 5’ end of HTR2A (see Fig. 3). We also found evidence that supports extensions of both untranslated regions, represented by the thinner blue bars at the terminal ends of the gene, and the addition of two exons (3a and 3b) for HTR2A. Note: The panoramic view of HTR2A-AS1, represented on the first lines of figures A and B, have exons enlarged approximately 30-fold relative to introns. The magnified loci between the red lines have exons and introns represented at a 1:1 scale. Arrows indicate the direction of transcription