Genetic variants in the upstream region of activin receptor IIA are associated with female fertility in Japanese Black cattle

Table 1 SNPs and a indel with genome-wide significant associations with ANAI₄ on BTA2

BTA	SNP and indel-ID	Reference SNP-ID_number^c	position (bp) _UMD3.1^d	allele_1^e	Minor allele frequency (upper extrame)	Minor allele frequency (lower extrame)	allele_2^f	odds ratio	P-value
2	BovineHD0200013961^b	rs110523739	48225372	G	0.45	0.29	A	1.98	6.52E-07
2	Hapmap43862-BTA-47538^a	rs41636186	48240577	A	0.45	0.29	G	1.98	6.52E-07
2	Hapmap43863-BTA-47554^a	rs41636197	48440885	G	0.45	0.29	A	1.96	8.32E-07
2	BovineHD4100001198^b	rs41636199	48443632	A	0.45	0.29	G	1.96	8.32E-07
2	g.48476925C>T		48476925	T	0.45	0.29	C	1.96	8.32E-07
2	g.48476943_48476946insGGC		48476943_48476946	GGC	0.45	0.29	(-)	1.96	8.32E-07

^aSNPs included in the Illumina Bovine SNP50K BeadChip; ^bImputed SNPs from the Illumina Bovine HD BeadChip. ^cReference SNP ID numbers (rs) were obtained using the SNPchiMp v.3 database (http://bioinformatics.tecnoparco.org/SNPchimp/). ^dThe positions are based on the UMD3.1 assembly of the bovine genome. ^eMinor allele; ^fMajor allele. The upper and lower extremes correspond to ANAI₄ values above the 85th percentile and below the 15th percentile, respectively

ISSN: 2730-6844