|
Approach
|
CHR
|
SNP
|
Location
|
Coded allele
|
Coded allele frequency
|
Z-score
|
P-value
|
Direction3
|
Closest gene4 within ±50kB
|
|---|
|
Baseline
|
| |
8
|
rs2440212
|
97270629
|
A
|
0.66
|
4.47
|
7.73×10−6
|
++++
|
(GDF6)
|
| |
9
|
rs13440434
|
131953827
|
A
|
0.87
|
−4.50
|
6.79×10−6
|
----
|
(GPR107)
|
| |
10
|
rs7087469
|
54339854
|
A
|
0.13
|
4.76
|
1.93×10−6
|
++?+
|
-
|
| |
13
|
rs9560521
|
89457392
|
A
|
0.13
|
4.69
|
2.69×10−6
|
++++
|
(LINC00559)
|
| |
16
|
rs8046816
|
71863525
|
A
|
0.47
|
4.53
|
5.92×10−6
|
++++
|
-
|
| |
20
|
rs17215529
|
3923402
|
A
|
0.85
|
4.79
|
1.66×10−6
|
++?+
|
RNF24
|
|
Averaged
|
| |
1
|
rs3100865
|
2795967
|
T
|
0.49
|
4.44
|
9.02×10−6
|
++++
|
-
|
| |
2
|
rs41379347
|
191577187
|
T
|
0.89
|
−4.58
|
4.57×10−6
|
??--
|
STAT1
|
| |
2
|
rs7602149
|
114357038
|
T
|
0.84
|
−4.57
|
4.78×10−6
|
--?-
|
LOC728055
|
| |
2
|
rs13001068
|
182706602
|
A
|
0.92
|
4.50
|
6.95×10−6
|
? + ?+
|
(PDE1A)
|
| |
7
|
rs697521
|
16730681
|
T
|
0.13
|
−4.74
|
2.12×10−6
|
--?-
|
BZW2
|
| |
8
|
rs7350109
|
60753909
|
A
|
0.81
|
−4.5
|
6.88×10−6
|
--?-
|
-
|
| |
11
|
rs1448128
|
121291660
|
C
|
0.24
|
−4.58
|
4.61×10−6
|
----
|
-
|
| |
22
|
rs5760767
|
23696411
|
T
|
0.51
|
4.58
|
4.62×10−6
|
++++
|
(TMEM211)
|
|
Repeated measures
|
| |
1
|
rs11590206
|
145665933
|
A
|
0.16
|
−4.72
|
2.33×10−6
|
----
|
(GJA5)
|
| |
2
|
rs41379347
|
191577187
|
T
|
0.89
|
−5.22
|
1.81×10−7
|
??--
|
STAT1
|
| |
2
|
rs7602149
|
114357038
|
T
|
0.84
|
−4.62
|
3.83×10−6
|
--?-
|
LOC728055
|
| |
4
|
rs13139186
|
96637940
|
T
|
0.90
|
−4.48
|
7.44×10−6
|
----
|
UNC5C
|
| |
4
|
rs233976
|
104823918
|
A
|
0.21
|
4.47
|
7.75×10−6
|
?+++
|
TACR3
|
| |
7
|
rs11771332
|
86539742
|
A
|
0.81
|
−4.48
|
7.45×10−6
|
?-?-
|
(KIAA1324L)
|
| |
9
|
rs2211185
|
1332721
|
T
|
0.77
|
4.55
|
5.42×10−6
|
++++
|
-
|
| |
18
|
rs2728505
|
21474070
|
A
|
0.55
|
−4.47
|
7.84×10−6
|
----
|
-
|
| |
22
|
rs5760767
|
23696411
|
T
|
0.51
|
4.54
|
5.68×10−6
|
++++
|
(TMEM211)
|
-
1filtered at ethnicity-specific minor allele frequency 5 %, where the SNP was present in at least two ethnicities, linkage disequilibrium R2 < 80 %, and heterogeneity p-value ≥ 0.1; 2Multi-Ethnic Study of Atherosclerosis; 3Order corresponding to direction positions: African, European, Chinese, Hispanic American; 4parentheses indicate location outside of gene
