| | |
Most strongly associated SNP in discovery
|
Most strongly associated SNP in validation
| |
|---|
|
BTCa
|
Interval (Mbp)b
|
SNP
|
Position (bp)
|
-log10 (P)
|
Effect ± SE
|
MAFc
|
\( \frac{\sigma_d^2}{\sigma_p^2} \) (%)d
|
SNP
|
Position (bp)
|
-log10 (P)
|
Effect ± SE
|
MAF
|
\( \frac{\sigma_d^2}{\sigma_p^2} \) (%)
|
Genese
|
|---|
|
2
|
95.312 - 95.730
|
rs136022579
|
95312328
|
4.920
|
155 ± 35.39
|
0.166
|
0.149
|
rs134324850
|
95725812
|
3.563
|
132 ± 36.23
|
0.171
|
0.197
|
ADAM23
|
|
3
|
97.907 - 98.799
|
rs43361287
|
98306933
|
4.351
|
82.29 ± 20.14
|
0.443
|
0.133
|
rs43363311
|
97907057
|
2.516
|
64.04 ± 21.6
|
0.427
|
0.139
|
AGBL4
|
|
5
|
71.878 - 71.878
|
rs110106971
|
71878168
|
4.947
|
−99.82 ± 22.71
|
0.332
|
0.158
|
rs110106971
|
71878168
|
2.012
|
55.58 ± 21.49
|
0.438
|
0.106
|
SYN3
f
|
|
26
|
32.249 - 32.341
|
rs42460360
|
32248251
|
4.185
|
129.5 ± 32.42
|
0.186
|
0.124
|
rs42741343
|
32336734
|
2.065
|
61.42 ± 23.36
|
0.349
|
0.110
|
LOC100847832
|
|
26
|
39.358 - 39.765
|
rs132810457
|
39358269
|
4.017
|
86.38 ± 22.13
|
0.343
|
0.122
|
rs110552548
|
39764774
|
2.239
|
−88.38 ± 32
|
0.214
|
0.125
|
GRK5
|
|
26
|
44.215 - 44.543
|
rs109406756
|
44537471
|
4.673
|
114.1 ± 26.83
|
0.244
|
0.143
|
rs134524557
|
44257893
|
2.246
|
70.3 ± 25.4
|
0.301
|
0.123
|
LHPP
|
|
27
|
42.674 - 42.890
|
rs41665573
|
42837186
|
5.248
|
−90.48 ± 19.92
|
0.469
|
0.164
|
rs41575082
|
42673983
|
2.328
|
62.09 ± 21.95
|
0.424
|
0.130
|
NA
|
-
aBTC: Bos Taurus chromosome
-
bIntervals containing individually validated SNPs are in bold
-
cMAF: minor allele frequency
-
d
σ
2
d
= dominance variance; σ
2
p
= phenotypic variance
-
eGenes with both top SNPs in discovery and validation inside them are in bold
-
fGenes with individually validated SNPs within them
