Exome sequencing of a family with lone, autosomal dominant atrial flutter identifies a rare variation in ABCB4 significantly enriched in cases

Table 1 Summary of Pedigree Members with Documented Cardiovascular Abnormalities

Generation	Subject ID	Age	Sex	Risk factor	Cardiovascular abnormality
III	2	86	Female	Hypertension	Atrial flutter
III	6	80	Male	Hypertension; alcohol abuse	Atrial flutter
IV	1	67	Male	Hypertension; smoking	Atrial flutter
IV	2	64	Male	Smoking	Atrial flutter
IV	3	63	Male	Smoking	Atrial flutter
IV	7	57	Male	---	Atrial flutter
IV	9	52	Male	---	Myocardial infarction

ISSN: 2730-6844