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Table 4 The effects of amino acids on lifespan of rsks-1 , gcn-2 , ife-2 , gas-1 , and mev-1 mutants

From: Mechanisms of amino acid-mediated lifespan extension in Caenorhabditis elegans

Strain Treatment % of N2 control mean lifespan % of untreated mean lifespan p-value # of worms Replicates
rsks-1(ok1255) Control 109   <0.001 362 4
1 mM tryptophan   71 <0.001 130 2
5 mM histidine   93 0.031 135 2
5 mM proline   94 0.042 140 2
10 mM serine   101 0.236 162 2
gcn-2(ok871) Control 90   <0.001 479 4
1 mM tryptophan   99 0.489 160 2
5 mM histidine   100 0.335 163 2
5 mM proline   107 0.001 205 2
10 mM serine   104 0.006 183 2
Ife-2(ok306) Control 97   0.245 112 2
1 mM tryptophan   94 0.029 138 2
5 mM histidine   98 0.597 110 2
5 mM proline   102 0.352 117 2
10 mM serine   99 0.791 96 2
gas-1(fc21) Control 69   <0.001 119 2
5 mM histidine   104 0.092 110 2
10 mM serine   98 0.327 106 2
5 mM proline   109 0.003 115 2
mev-1(kn1) Control 69   <0.001 273 2
5 mM histidine   104 0.021 215 2
10 mM serine   109 <0.001 258 2
5 mM proline   102 0.102 256 2