Table 3 Association between the TCF7L2 rs7903146 SNP and anthropometric, biochemical and clinical parameters in non-T2D subjects in the ISOR study
From: The TCF7L2rs7903146 polymorphism, dietary intakes and type 2 diabetes risk in an Algerian population
Parameter | CC | CT | TT | p |
|---|---|---|---|---|
(n = 228) | (n = 287) | (n = 129) | ||
Weight (kg) | 72.1 ± 14.0 | 70.7 ± 15.2 | 67.7 ± 14.1 | 0.02 |
BMI (kg/m2) | 26.4 ± 5.0 | 25.7 ± 5.1 | 24.9 ± 5.1 | 0.009 |
Waist (cm) | 88.1 ± 12.2 | 86.1 ± 12.2 | 84.3 ± 11.9 | 0.01 |
Hip (cm) | 102.5 ± 9.7 | 101.6 ± 9.6 | 100.6 ± 9.9 | 0.06 |
Waist-to-hip ratio | 0.86 ± 0.09 | 0.85 ± 0.08 | 0.84 ± 0.08 | 0.02 |
Fasting glucose (mmol/L) | 4.80 ± 0.50 | 4.75 ± 0.50 | 4.82 ± 0.49 | 0.34 |
Fasting insulin (μIU/mL) | 8.58 ± 6.67 | 7.91 ± 5.40 | 6.88 ± 4.00 | 0.25 |
HOMA-IR | 1.8 ± 1.4 | 1.7 ± 1.2 | 1.5 ± 0.9 | 0.36 |
HOMA-B | 160.9 ± 172.5 | 144.7 ± 112.1 | 114.4 ± 72.9 | 0.08 |
Triglycerides (mmol/L) | 1.14 ± 0.49 | 1.14 ± 0.45 | 1.02 ± 0.47 | 0.24 |
Total cholesterol (mmol/L) | 4.43 ± 0.93 | 4.46 ± 0.89 | 4.38 ± 0.89 | 0.95 |
HDL-cholesterol (mmol/L) | 1.25 ± 0.32 | 1.24 ± 0.29 | 1.30 ± 0.34 | 0.53 |
LDL-cholesterol (mmol/L) | 2.67 ± 0.86 | 2.71 ± 0.85 | 2.64 ± 0.84 | 0.84 |
SBP (mmHg) | 122.0 ± 16.2 | 122.5 ± 18.1 | 121.5 ± 16.9 | 0.23 |
DBP (mmHg) | 75.9 ± 9.1 | 76.5 ± 10.8 | 76.2 ± 9.5 | 0.08 |