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Table 1 Clinical characteristics of the study population

From: Association of dopaminergic pathway gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes

Characteristics DMa (n = 225) CRIb (n = 196) P
Gender (M/F) 76/149 65/131 0.89d
Age (years) 60.6 ± 11.5 57 ± 12.8 0.10c
BMI (kg/m2) 23.1 ± 0.3 23.4 ± 0.2 0.00
Duration of Diabetes (years) 17.07 ± 6.69 10.4 ± 7.7 <0.05 c
Hb A1c (%) 7.3 ± 1.0 7.5 ± 1.1 0.949c
Systolic pressure (mm Hg) * 140 (106–190) 150 (110–210) 0.002e
Diastolic pressure (mm Hg) * 84 (80–104) 90 (70–110) 0.025e
Serum creatinine (μmol/l) * 84 (35–108) 177 (124–1112) <<0.05 e
UAER (mg/liter)* 10 (1–16) 864 (320–1584) <<0.05 e
GFR (mls/min/1.73 m 2 ) 81.44 ± 21.85 27.83 ± 24 <<0.05 c
Serum triglyceride (mmol/l) 1.7 ± 0.67 1.8 ± 1.4 0.307c
Serum cholesterol (mmol/l) 4.8 ± 0.97 4.9 ± 0.92 0.852c
Retinopathy (%) Non-proliferative (%) Proliferative (%) 24 15 09 88 35 53 <<0.05 d
Cardiovascular events (%) 3 8.3  
  1. Data presented as mean ± SD (* median and range). atype-2 diabetes subjects without nephropathy (DM); b with diabetic renal insufficiency (CRI); c Student's t test; d Pearson's χ2 test; e Mann-Whitney U test.