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Table 2 SNPs according to position, function, predicted changes in amino acid and novelty.

From: Single nucleotide polymorphisms (SNPs) in coding regions of canine dopamine- and serotonin-related genes

Gene CFA* Region Allel Function† Codon position Protein residue‡ Aa position Novelty of SNP§ Reference sequence||
TH 18 EX 13 C/T syn 3 Asp [D] 482 Novel [GenBank: NM_001002966.1]
SLC6A3 34 EX 9 A/G syn 3 Gly [G] 418 Novel [GenBank: XM_846543.1]
   EX 10 C/T syn 3 Asp [D] 468 Publ. – rs23877306 [GenBank: XM_846543.1]
   EX 10 A/G syn 3 Ala [A] 471 Novel [GenBank: XM_846543.1]
   EX 11 C/T syn 3 Asp [D] 498 Novel [GenBank: XM_846543.1]
DRD1 4 EX 1 A/G syn 3 Ala [A] 84 Novel [GenBank: XM_546227.2]
   EX 1 C/T syn 3 Gly [G] 88 Novel [GenBank: XM_546227.2]
   EX 1 C/T syn 3 Val [V] 236 Novel [GenBank: XM_546227.2]
   EX 1 C/T ns 2 Thr [T]/Met [M] 354 Novel [GenBank: XM_546227.2]
DRD2 5 EX 2 C/T syn 3 Asn [N] 23 Novel [GenBank: NM_001003110.1]
   EX 2 C/T syn 3 Ala [A] 77 Novel [GenBank: NM_001003110.1]
DRD3 33 EX 4 C/T syn 3 Cys [C] 231 Novel [GenBank: XM_545106.2]
   EX 6 A/G ns 2 Gln [Q]/Arg [R] 294 Novel [GenBank: XM_545106.2]
   EX 6 C/T ns 1 Leu [L]/Phe [F] 341 Novel [GenBank: XM_545106.2]
   EX 7 C/T syn 3 Cys [C] 402 Novel [GenBank: XM_545106.2]
DBH 9 EX 1 A/G syn 3 Thr [T] 17 Novel [GenBank: NM_001005263.1]
   EX 2 A/G syn 3 Gln [Q] 121 Novel [GenBank: NM_001005263.1]
   EX 3 C/T syn 3 Tyr [Y] 163 Novel [GenBank: NM_001005263.1]
   EX 4 A/C ns 3 Lys [K]/Asn [N] 263 Novel [GenBank: NM_001005263.1]
   EX 4 C/T syn 3 Gly [G] 297 Novel [GenBank: NM_001005263.1]
   EX 12 A/G syn 3 Gly [G] 622 Novel [GenBank: NM_001005263.1]
HTR1A 2 EX1 A/C ns 1 Lys [K]/Gln [Q] 270 Publ. – rs22855024 [GenBank: XM_544358.1]
HTR1B 12 EX 1 A/C ns 1 Ile [I]/Leu [L] 53 Novel [GenBank: NM_001006948.1]
   EX 1 A/G syn 3 Pro [P] 82 Novel [GenBank: NM_001006948.1]
HTR1D 2 EX 1 C/T ns 2 Ala [A]/Val [V] 97 Novel [GenBank: NM_001003280.1]
   EX 1 C/T syn 3 Tyr [Y] 221 Novel [GenBank: NM_001003280.1]
   EX 1 A/G ns 2 Glu [E]/Gly [G] 263 Publ. – rs22791523 [GenBank: NM_001003280.1]
   EX 1 C/T syn 3 His [H] 372 Novel [GenBank: NM_001003280.1]
HTR1E 12 EX 1 C/T syn 1 Leu [L] 39 Novel [GenBank: XM_539028.1]
HTR1F 31 EX 1 C/T syn 3 Arg [R] 162 Publ. – rs9250875 [Ensembl: ENSCAFT00000012417]
HTR2B 25 EX 1 C/T ns 2 Thr [T]/Ile [I] 88 Novel [GenBank: NM_001024633.1]
   EX 3 C/T ns 2 Ala [A]/Val [V] 431 Novel [GenBank: NM_001024633.1]
HTR2C X EX 6 A/G syn 3 Pro [P] 280 Novel [GenBank: NM_001006648.1]
HTR3A 5 EX 2 C/T ns 2 Thr [T]/Met [M] 64 Novel [GenBank: XM_546517.2]
  1. * Chromosome number, Canis familiaris.
  2. † Synonymous SNP (syn) and non-synonymous SNP (ns)
  3. ‡ Listed ambiguity is decided by the respective allel in column 4.
  4. § Novelty of SNPs explored by blasting the dbSNP (Dog_9615) at [36]. Reference no. given for corresponding published SNP.
  5. || Canine sequence/predicted sequence, for defining SNPs position in protein. Given as GenBank or Ensemble accession number.
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BMC Genomic Data

ISSN: 2730-6844

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