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Table 3 Genes with a significantly high weighted-average F ST (P ≤ 0.05)

From: Patterns of population differentiation of candidate genes for cardiovascular disease

Symbol Gene name YRI vs. CEU YRI vs. CHB + JPT CEU vs. CHB + JPT Biological processes
   F ST P F ST P F ST P  
GRB2 growth factor receptor-bound protein 2 0.720 0.035* 0.828 0.023* 0.048 0.556 Immune response
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.658 0.043* 0.555 0.071 0.034 0.605 Immune response
IL4 interleukin 4 0.262 0.220 0.205 0.329 0.512 0.043* Immune response/Apoptosis
IL6 interleukin 6 0.108 0.478 0.431 0.119 0.570 0.037* Immune response/Apoptosis
ARHGEF1 Rho guanine nucleotide exchange factor 1 0.769 0.030* 0.532 0.078 0.149 0.263 Apoptosis
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.642 0.045* 0.544 0.074 0.070 0.456 Apoptosis
BCL2L1 BCL2-like 1 0.278 0.204 0.679 0.043* 0.265 0.127 Apoptosis
PMVK phosphomevalonate kinase 0.563 0.059* 0.652 0.048* 0.097 0.380 Lipoprotein metabolism
F2 coagulation factor II 0.413 0.109 0.536 0.077 0.473 0.049* Blood clotting
  1. * Genes with a significantly higher weighted-average F ST