Table 2 Summary of significant findings of GSMA and CPMM
chromosome | GSMA | CPMM | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
30 cM bin | previous reports | location | SR analysis | MC-Replications n (%) from 333* | p-value for whole chromosome | ||||||
pSR | pSR-weight | SR* | Ranks* | < 1% | 1%–5% | 5%–10% | |||||
1 | 3th | Hicks (LOD = 4.9) | 58 – 87 cM | 0.498 | 0.661 | 298 | 8 – 118 | -- | -- | -- | 0.007 |
4th | 87 – 116 cM | 0.050 | 0.055 | 430 | 51 – 117 | -- | 333 100% | -- | |||
2 | 4th | Martinez (MLS = 2.0) | 89 – 120 cM | 0.220 | 0.147 | 358 | 39 – 115 | -- | -- | -- | 0.250 |
5th | 120 – 149 cM | 0.183 | 0.096 | 368 | 7 – 118 | -- | -- | 8 2% | |||
7th | Pankratz (LOD = 2.5) | 179 – 209 cM | 0.447 | 0.427 | 308 | 51 – 73 | -- | -- | -- | ||
5 | 5th | Hicks (LOD = 1.6) | 113 – 141 cM | 0.094 | 0.099 | 399 | 49 – 125 | -- | 18 5% | 315 95% | 0.108 |
6th | Scott (MLOD = 2.4) | 142 – 169 cM | 0.036 | 0.034 | 506 | 51 – 118 | -- | 333 100% | -- | ||
3rd-60 cM | Martinez (MLS = 1.1) | 132 – 198 cM | 0.019 | 0.014 | 224.5 | 24.5 – 58 | -- | 304 91% | 29 9% | ||
8 | 1st | Scott (MLOD = 2.0) | 0 – 28 cM | 0.131 | 0.208 | 384.5 | 14.5 – 117 | -- | -- | -- | 0.331 |
9 | 6th | DeStefano (MLS = 1.3) | 140 – 169 cM | 0.015 | 0.012 | 461 | 55 – 114 | -- | 333 100% | -- | 0.321 |
3rd-60 cM | 112 – 169 cM | 0.035 | 0.238 | 215 | 16 – 58 | -- | 332 99% | 1 <1% | |||
14 | 5th | 110 – 138 cM | 0.036 | 0.047 | 434 | 51 – 115 | -- | 333 100% | 0.300 | ||
X | Pankratz (LOD = 2.5) | ---- not in GSMA analysis --- | 0.002 | ||||||||