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Table 1 Allelic variants in the coding sequence of ENaC subunits in Dahl S, R, Wistar, and Brown Norway rats

From: Sequence analysis of coding and 3' and 5' flanking regions of the epithelial sodium channel α, β, and γ genes in Dahl S versus R rats

Subunit Nucleotide position/exon Dahl S and R Wistar Brown Norway AA change
ENaC α +225/1 TT TT* GG D75E
  +10716/3 AA AA GG, GA, AA R290R
ENaC γ +4008/4 GG GG AA, AG, GG E255K
  +22549/7 CC TT, TC, CC TT, TC, CC D376D
  +24672/8 CC TT, TC, CC TT, TC, CC C410C
  +29195/13 TT CC, CT, TT CC, CT, TT C542C
  +29291/13 TT GG, GT, TT GG, GT, TT C573W
  1. Numbering starts at the A nucleotide of the primary initiation codon [15].
  2. AA: amino acid
  3. * GG genotype was previously reported [5].