Skip to main content

Table 1 Allelic variants in the coding sequence of ENaC subunits in Dahl S, R, Wistar, and Brown Norway rats

From: Sequence analysis of coding and 3' and 5' flanking regions of the epithelial sodium channel α, β, and γ genes in Dahl S versus R rats

Subunit

Nucleotide position/exon

Dahl S and R

Wistar

Brown Norway

AA change

ENaC α

+225/1

TT

TT*

GG

D75E

 

+10716/3

AA

AA

GG, GA, AA

R290R

ENaC γ

+4008/4

GG

GG

AA, AG, GG

E255K

 

+22549/7

CC

TT, TC, CC

TT, TC, CC

D376D

 

+24672/8

CC

TT, TC, CC

TT, TC, CC

C410C

 

+29195/13

TT

CC, CT, TT

CC, CT, TT

C542C

 

+29291/13

TT

GG, GT, TT

GG, GT, TT

C573W

  1. Numbering starts at the A nucleotide of the primary initiation codon [15].
  2. AA: amino acid
  3. * GG genotype was previously reported [5].