| SLINK/SUP | SIMLA | ALLEGRO |
---|---|---|---|
Simulates on pedigrees as they have been collected | Yes | No | Yes |
Simulates marker data conditional on | Â | Â | Â |
   1) observed affection status | Yes | Yes | Yes |
   2) observed affection status and observed exposure/liability class | Yes | No | No |
   3) observed quantitative trait values | Yes | No | No |
Simulates LD between | Â | Â | Â |
   1) marker loci | Yes | Yes | No |
   2) marker and trait loci | Yes | Yes | No |
Simulates values for | Â | Â | Â |
   1) affection status | Yes | Yes | No |
   2) environmental exposure | No | Yes | No |
   3) quantitative trait | Yes | Yes | No |
   4) covariates | No | Yes | No |
Simulates multi-locus susceptibility between | Â | Â | Â |
   1) unlinked loci | Yes (indirectly) | Yes | No |
   2) linked loci | No/Future | Yes | No |
Simulates under sex-specific maps | Yes | No | Yes |
Simulates X-linked genetic data | Yes/Future | No | Yes |
Simulates upon pedigrees with loops | Few | No | Yes |
Pedigree restrictions | 16 founders | 4 founders | < 31 bits†|