Segregation analysis of apolipoprotein A1 levels in families of adolescents: A community-based study in Taiwan

BMC Genomic Data

Table 3 Parameter estimates from segregation analysis of residual Apo A1 levels under Class D regressive models, conditional on proband phenotypes

Model	Sporadic	Familial correlations	Environmental	Mendelian	General
qA	[1]	[1]	0.974	0.854	0.976
τAA	-	-	=qA	[1]	0.971
τAB	-	-	=qA	[0.5]	0.989
τBB	-	-	=qA	[0]	1.000
AA	118.0	118.4	115.8	118.2	115.9
AB	= AA	= AA	167.2	114.2	167.3
BB	= AA	= AA	287.7	195.9	287.8
σ²	492.9	493.2	331.9	390.3	333.3
ρMF	[0]	0.240	0.302	0.267	0.301
ρMO	[0]	0.129	0.263	0.204	0.266
ρFO	[0]	0.081	0.148	0.149	0.148
ρSS	[0]	0.000	0.114	0.088	0.115
Parameter #	2	6	9	9	12
-2ln(L)	6453.22	6435.17	6327.62	6361.51	6327.32
AIC	6457.22	6447.17	6345.62	6370.51	6351.32
χ²	125.9	107.85	0.30	34.19	-
P	0.000	0.000	0.960	0.000	-

Abbreviation: #, number of parameters; SEM, standard error of mean; qA, gene frequency; τAA, τAB, τBB, transmission probability; μAA, μAB, μBB, genotype means; σ², variance; ρMF, ρMO, ρFO, ρSS, correlation coefficients among spouse, mother-offspring, father-offspring and sibling pairs; #, number of parameters; ln(L), logarithm of likelihood; AIC, Akaike information criteria; P, significance level compared with the unrestricted general model.

ISSN: 2730-6844