Figure 4
From: A mosaic genetic screen for novel mutations affecting Drosophila neuroblast divisions
The D76 mutation affects cell proliferation and Miranda localization. (A-C) Miranda but not Inscuteable crescents are lost in D76 clone neuroblasts. DNA staining (blue); Inscuteable (red, A, A'); Miranda (red, B-C'); CD8::GFP (green, A', B', C'); Bar: 10 μm. Although a crescent of Inscuteable (A, A') forms correctly in D76 neuroblast clones, Miranda crescents are never observed (B, B', C, C'); occasionally Miranda localization to spots in the cytoplasm is observed (arrows in C, C').