Table 2 C4A and C4B gene dosage in a healthy cohort determined by the presented qPCR method. Comparison to earlier data obtained by Southern-blot analysis [28]
From: Real-time PCR quantification of human complement C4A and C4B genes
C4A genes | C4B genes | ||||
|---|---|---|---|---|---|
Gene dosage | Present work | Published data | Gene dosage | Present work | Published data |
| Â | Number (%) | Â | Number (%) | ||
0 | 2 (1.7) | 2 (1.6) | 0 | 1 (0.8) | 1 (0.8) |
1 | 18 (15.3) | 26 (20.3) | 1 | 24 (20.3) | 26 (20.3) |
2 | 65 (55.1) | 73 (57.0) | 2 | 75 (63.6) | 90 (70.3) |
3 | 30 (25.4) | 24 (18.8) | 3 | 18 (15.3) | 10 (7.8) |
4 | 3 (2.5) | 3 (2.3) | 4 | 0 (0.0) | 1 (0.8) |
Total | 118 (100) | 128 (100) | Â | 118 (100) | 128 (100) |
χ2 test | p = 0.7023 |  | p = 0.3632 | ||