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Table 1 Average Zlr z-score (over 100 replicates) using multipoint and weighted conditional analysis

From: Linkage analysis of GAW14 simulated data: comparison of multimarker, multipoint, and conditional approaches

  

Danacaa

Karangar

Aipotu

  

Maximum z

z at true location

Maximum z

z at true location

Maximum z

z at true location

Chr

Conditioning weightsA

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Mean

SD

1

Unweighted

4.83

0.89

4.52

0.96

2.35

0.72

1.32

1.14

2.70

0.74

2.08

0.97

 

Weights 0–1

-b

-

3.30

1.07

-

-

0.73

1.12

-

-

1.49

0.96

 

Weights 1–0

-

-

2.09

1.18

-

-

0.80

1.06

-

-

1.18

0.95

 

Weights NPL

-

-

2.95

1.00

-

-

0.67

1.09

-

-

1.30

1.05

 

Max weights

-

-

3.55

0.90

-

-

1.39

0.89

-

-

1.99

0.74

3

Unweighted

3.99

1.05

3.92

1.11

3.06

0.81

2.80

1.03

3.36

0.97

3.20

1.06

 

Weights 0–1

-

-

3.13

1.10

-

-

1.91

1.07

-

-

2.31

1.04

 

Weights 1–0

-

-

2.19

1.12

-

-

2.02

0.94

-

-

2.09

1.19

 

Weights NPL

-

-

2.74

1.19

-

-

1.51

1.06

-

-

1.94

1.01

 

Max weights

-

-

3.43

1.02

-

-

2.56

0.79

-

-

2.91

0.93

  1. aWeights 0–1, 1–0 and NPL are described by Cox et al. [3], where Weights NPL is called weightPROP. Max weights corresponds to the maximum Zlr under the 0–1, 1–0, and NPL weighting schemes.
  2. b-, results not calculated.