Table 2 Synthetic interactions with BNI4, CHS1, CHS3, CHS4, CHS5, CHS6 and CHS7.
From: An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae
Functional category | Gene | Interacting partners |
|---|---|---|
Cell wall maintenance | BCK1 | BNI4, CHS1, CHS3, CHS4, CHS5, CHS7 |
| Â | FKS1, SLT2, SMI1 | BNI4, CHS3, CHS4, CHS5, CHS6, CHS7 |
| Â | YPL261C | CHS1 |
| Â | ECM21 | CHS1, CHS5 |
| Â | CHS2 | CHS3 |
| Â | SWI4 | CHS3, CHS4, CHS5 |
| Â | CCW12, GAS1, YLR111W | CHS3, CHS4, CHS5, CHS7 |
| Â | TUS1 | CHS4, CHS5, CHS7 |
| Â | DAN3, PAT1 | CHS5 |
Cell polarity & vesicular transport | NBP2, RGD1, SHS1, SPA2 | BNI4 |
| Â | EDE1, MYO2, RVS167, VRP1 | BNI4, CHS3, CHS4, CHS5, CHS7 |
| Â | ARC40, ARP2 | BNI4, CHS3, CHS4, CHS5, CHS6, CHS7 |
| Â | BNI1 | BNI4, CHS3, CHS4, CHS7 |
| Â | RVS161 | BNI4, CHS5 |
| Â | CYK3 | BNI4, CHS7 |
| Â | BUD20, VPS5, VPS17, VPS29, VPS35 | CHS1 |
| Â | HBT1 | CHS1, CHS3 |
| Â | ARC18 | CHS1, CHS3, CHS4, CHS5, CHS6 |
| Â | EMP24 | CHS1, CHS3 |
| Â | BEM4, PEA2 | CHS1, CHS5 |
| Â | CDC3, CDC11, IES6, SRV2, VAM7 | CHS3 |
| Â | CDC12 | CHS3, CHS4 |
| Â | FAB1 | CHS3, CHS4, CHS5 |
| Â | CLA4 | CHS3, CHS4, CHS5, CHS6, CHS7 |
| Â | SAC6, SLA1, TPM1 | CHS3, CHS4, CHS5, CHS7 |
| Â | YLR338W | CHS3, CHS4, CHS6 |
| Â | SHE4, SMY1 | CHS3, CHS4, CHS7 |
| Â | VPS24, VPS67 | CHS3, CHS5 |
| Â | AST1, LST4, YPK1 | CHS4 |
| Â | SEC22 | CHS4, CHS5 |
| Â | AOR1, HSE1, VPS21 | CHS5 |
Suspected role in cell polarity & vesicular transport | YPL066W | BNI4 |
| Â | ILM1 | BNI4, CHS3, CHS4, CHS6 |
| Â | SPF1 | CHS1, CHS4 |
| Â | YGL081W | CHS1, CHS5 |
| Â | YBR077C | CHS3 |
| Â | GUP1 | CHS3, CHS4, CHS5, CHS6 |
| Â | OPI3 | CHS3, CHS4, CHS7 |
| Â | LSM6 | CHS5 |
| Â | IST3 | CHS6 |
Protein modification | VAN1 | BNI4, CHS3, CHS4, CHS5, CHS6, CHS7 |
| Â | YGL110C | CHS1 |
| Â | ANP1, BTS1, MNN2, MNN9 | CHS3 |
| Â | MNN10 | CHS3, CHS4, CHS5, CHS6, CHS7 |
| Â | UBI4 | CHS3, CHS5, CHS6 |
| Â | UBP13 | CHS4 |
| Â | BRE1 | CHS5 |
| Â | UFD4 | CHS5 |
| Â | MNN11 | CHS5, CHS6 |
| Â | LAS21 | CHS6 |
Ribosomal function/cell size | LGE1 | CHS1, CHS3, CHS5 |
| Â | RPL20B | CHS3 |
| Â | RPS8A | CHS3, CHS4, CHS5 |
| Â | ASC1 | CHS3, CHS5 |
| Â | RSA1 | CHS4 |
| Â | RPL14A | CHS5 |
Cell cycle | CLN2 | CHS1 |
| Â | CDC26, DOC1 | CHS3 |
| Â | YNL171C | CHS3, CHS5 |
| Â | CLB3, CTK2 | CHS5 |
Mitochondrial function | MDM38, NUC1, UTH1, YME1 | CHS1 |
| Â | YFR045W | CHS1, CHS5 |
| Â | MST1, TOM37 | CHS3 |
| Â | YTA12 | CHS3, CHS4 |
| Â | ATP17 | CHS4 |
| Â | RPO41 | CHS4, CHS6, CHS7 |
| Â | COQ2, COX11, LAT1, MDM12, PET8, SHE9 | CHS5 |
Carbohydrate and lipid metabolism | DEP1, ELO1, HXT8, IPK1, PDA1, PDC1, PFK2, PHO5, PKR1, RPE1, TYR1, YDR248C | CHS1 |
Other functions | BRE5 | BNI4, CHS3, CHS4 |
| Â | IXR1 | BNI4, CHS5 |
| Â | CNB1, HAP2, HIT1, PEX22, PMP3, PRM3, SKI2, WHI2 | CHS1 |
| Â | RPA34 | CHS1, CHS3, CHS4, CHS5, CHS7 |
| Â | FPS1 | CHS1, CHS4, CHS5 |
| Â | GRS1, LEA1, MRE11 | CHS1, CHS5 |
| Â | CSF1 | CHS3, CHS4, CHS5 |
| Â | PRE9 | CHS3, CHS5, CHS7 |
| Â | MUM2 | CHS3, CHS6 |
| Â | UME6 | CHS4, CHS6 |
| Â | DOT1, PDE2, PEX14, SWI3 | CHS5 |
| Â | IRA2 | CHS5, CHS6 |
| Â | NUP133 | CHS5, CHS6, CHS7 |
| Â | MSN5 | CHS6 |
| Â | PEX6 | CHS7 |
Unknown function | YBR209W, YDR314C, YEL033W, YIL110W, YMR003W, YNL179C, YOR322C, YPR053C | CHS1 |
| Â | YDL206W | CHS1, CHS5 |
| Â | YDL032W | CHS3 |
| Â | YDL033C | CHS3, CHS5 |
| Â | YGL152C | CHS5 |
| Â | YNL235C | CHS6 |
| Â | YIL121W | CHS7 |