Table 3 Comparison of linkage results for subjects in G2 (R4) versus in G3 (R1 and R2)
From: An autosome-wide search using longitudinal data for loci linked to type 2 diabetes progression
Ch # | Phenotype Group Rate: Age | Location | Distance (cM) | Most Significant Marker | Most Significant P-value | |
|---|---|---|---|---|---|---|
1 | R4G2: 43–47 | q25 ~ q32 | 176 ~ 218 | GATA48B01 | A 5.21 × 10 -8 | |
R2G3: 51–55 | p31.1 ~ p22.1 | 114 ~ 137 | ATA29D04 | 0.0074 | ||
G3 – Mean | p31.1 ~ p22.1 | 114 ~ 140 | ATA2E04 | 0.0074 | ||
3 | R4G2: 43–47 | p26.3 ~ p21.31 | 6 ~ 71 | GATA164B08 | 1 × 10 -11 | |
G3 – Mean | p14.1 ~ q12.3 | 91 ~ 119 | GATA128C02 | 0.0049 | ||
8 | R4G2: 43–47 | q23.1 ~ q24.13 | 119 ~ 135 | GATA7G07 | 2.94 × 10 -6 | |
R1G3: 43–51 | q24.13 ~ q24.22 | 135 ~ 148 | GATA21C12 | 0.0025 | ||
R2G3: 51–55 | q24.13 ~ q24.22 | 135 ~ 148 | GATA21C12 | B 1.06 × 10 -4 | ||
9 | R4G2: 43–47 | p24.1 ~ p21.3 | 14 ~ 44 | GATA27A11 | 7.0 × 10 -7 | |
11 | R4G2: 43–47 | p15.5 ~ p15.2 | 2 ~ 21 | GATA23F06 | 9.9 × 10-4 | |
q22.3 ~ q24.3 | 101 ~ 131 | GATA23E06 | 3.14 × 10 -4 | |||
G2 – Mean | q12.1 ~ q13.5 | 56 ~ 76 | GATA90D07 | 0.0090 | ||
G3 – Mean Glucose | p14.1 ~ q12.3 | 91 ~ 119 | GATA30G01 | 6.6 × 10 -4 | ||
18 | R4G2: 43–47 | p11.31 ~ q22.1 | 13 ~ 107 | GATA26C03 | < 10 -11 | |
R1G3: 43–51 | p11.31 | 3 ~ 7 | 321xc9 | 0.007 | ||
R2G3: 51–55 | q21.2 ~ q21.32 | 80 ~ 89 | ATA7D07 | 0.0059 |