Figure 2
From: Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations
The relationship between integer copy number (x-axis) and average log uric acid concentrations is approximately linear. Slopes for the copy number coefficients at the chromosome 4 CNP-9 Mb (top) and CNP-10 Mb (bottom) loci overlay the empirical average log uric acid concentration with error bars drown to ± two standard errors of the mean. The opposite signs of the regression slopes at CNP-9Mb and CNP-10Mb is a reflection of linkage disequilibrium – the copy number estimates have a strong, negative correlation (Spearman correlation = -0.82).