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Table 3 Results of significant 1 allele substitution effects P-value

From: Associations between variants of FADS genes and omega-3 and omega-6 milk fatty acids of Canadian Holstein cows

Trait   SNP2   Estimate ± SE3 P-values FDR4
Fatty acid Common name Lab Id rs#    P-values
Polyunsaturated fatty acids
C18:2n9c11t CLA:9c11t FADS2-19 rs210169303 -0.0176 ± 0.0083 0.036 0.248
C18:2n10t12c CLA:10t12c FADS2-19 rs210169303 -0.0012 ± 0.0005 0.010 0.069
C18:2n6cc Linoleic acid FADS1-07 rs42187261 -0.0410 ± 0.0197 0.038 0.137
   FADS1-08 rs41652284 -0.0468 ± 0.0226 0.039 0.137
C18:2n6tt Trans linoleic acid FADS1-07 rs42187261 0.0069 ± 0.0033 0.036 0.126
   FADS2-19 rs210169303 -0.0083 ± 0.0034 0.016 0.109
C20:3n6 Dihomogamma linolenic acid FADS1-01 rs136261927 -0.0087 ± 0.0021 0.000 0.0004
  FADS1-07 rs42187261 0.0037 ± 0.0017 0.032 0.055
  FADS1-08 rs41652284 -0.0044 ± 0.0020 0.027 0.055
   FADS2-23 rs109772589 -0.0080 ± 0.0021 0.0002 0.001
C20:4n6 Arachidonic acid FADS1-07 rs42187261 0.0042 ± 0.0016 0.009 0.032
   FADS2-23 rs109772589 -0.0071 ± 0.0020 0.0004 0.003
C20:5n3 Eicosapentaenoic acid FADS1-07 rs42187261 0.00420 ± 0.0008 0.0036 0.039
Monounsaturated fatty acids
C14:1 t Myristelaidic acid FADS2-05 rs211263660 0.0092 ± 0.0046 0.047 0.256
C18:1n9c Oleic acid FADS1-07 rs42187261 -0.7529 ± 0.2889 0.009 0.067
C18:1 total   FADS1-07 rs42187261 -0.7697 ± 0.3023 0.011 0.079
Total MUFA   FADS1-07 rs42187261 -0.8044 ± 0.3445 0.020 0.141
Saturated fatty acids
C6:0 Caproic acid FADS1-07 rs42187261 0.0215 ± 0.0110 0.050 0.353
C8:0 Caprylic acid FADS1-07 rs42187261 0.0246 ± 0.0108 0.023 0.158
C10:0 Caprinic acid FADS1-07 rs42187261 0.087 2 ± 0.0382 0.023 0.161
C11:0 Undecanoic acid FADS1-07 rs42187261 0.0111 ± 0.0041 0.008 0.053
C12:0 Lauric acid FADS1-07 rs42187261 0.1249 ± 0.0525 0.018 0.125
C16:0 Palmitic acid FADS1-01 rs136261927 0.6519 ± 0.3287 0.048 0.084
   FADS1-07 rs42187261 0.5063 ± 0.2555 0.048 0.084
   FADS2-05 rs209202414 -0.5908 ± 0.2473 0.017 0.079
   FADS2-19 rs210169303 0.6281 ± 0.2746 0.023 0.079
C23:0 Tricosanoic acid FADS1-07 rs42187261 0.0021 ± 0.0008 0.006 0.044
Total SFA   FADS1-07 rs42187261 0.8069 ± 0.3549 0.024 0.165
  1. 1For significant associations, P-values and FDR P-values (P≤0.05) are shown. Reference genotype is either CC or GG.
  2. 2Lab Id = lab notation of SNPs, rs# = SNP data base identification number of SNPs.
  3. 3Estimate = g/100 g of total fat, SE = Standard error.
  4. 4FDR = False discovery rate.