A new locus on chromosome 22q13.31 linked to recessive genetic epilepsy with febrile seizures plus (GEFS+) in a Tunisian consanguineous family

Table 1 Clinical characteristics of affected individuals

Subject (sex, age) ^*	FS		AFS		EEG	Neurological examination	MRI	Treatment/age
Subject (sex, age) ^*	Onset age/remission, age	n	Onset age/remission, age	Type/n	EEG	Neurological examination	MRI	Treatment/age
IV-2 (F, 13 y)	4 y/yes, 10 y	4	7 y/8 y	GTCS/3	Normal	Normal	Normal	VPA/7 y-until now
IV-3 (M, 18 y)	2 y/yes, 13 y	Numerous	3 y/7 y	GTCS/1 yearly	Normal	Normal	Normal	VPA/8 y-12 y
IV-3 (M, 18 y)	2 y/yes, 13 y	Numerous	8 y/9 y	A/numerous	Normal	Normal	Normal	VPA/8 y-12 y
IV-4 (M, 17 y)	2 y/no	Numerous	6 y/11 y	GTCS/5	3 Hz generalized SW	Mild mental retardation	Normal	VPA/5 y-until now
IV-4 (M, 17 y)	2 y/no	Numerous	6 y/11 y	A/numerous	3 Hz generalized SW	Mild mental retardation	Normal	VPA/5 y-until now

^*All individuals were agree to publish clinical details.
M: Male, F: Female, y: years, FS: Febrile Seizures, AFS: Afebrile Seizures, n: Seizures number, EEG: Electroencephalogram, GTC: Generalized Tonico Clonic Seizures, A: Absence, SW: Spike Wave, MRI: Magnetic Resonance Imaging, VPA: Valproic Acid.

ISSN: 2730-6844