Comparison between Europe and East Asia specific signals of selection. At each putative hit, we further explored the origin of the signal by analyzing each continent in turn while holding all other data constant. Only the two best-represented continents, Europe and East Asia, yield meaningful signals. Panels depict –log10P in Europe plotted against –log10P for East Asia under the CS = 0 for each of the four climate variables (Pr = precipitation, rH = relative humidity, T = temperature, and Sr = solar radiation). The lack of strong correlation suggests a tendency for climate-based selection to have operated independently and largely on different subsets of genes in the different geographic regions.