Skip to main content

Table 3 Predictors of DNA Yield (log_e transformed) in mothers

From: Predictors of mother and child DNA yields in buccal cell samples collected in pediatric cancer epidemiologic studies: a report from the Children’s Oncology group

  HB (N = 446) Infant leukemia (N = 489) Combined (N = 935)
  βa % changeb Pvalue βa % changeb Pvalue βa % changeb Pvalue
Age at DNA collection (years)         
< 30 years Reference Reference   Reference Reference   Reference Reference  
30 – 35 years 0.06 (−0.35-0.47) 6.2 0.78 −0.25 (−0.67-0.16) −22 0.23 −0.11 (−0.41-0.18) −10 0.45
35 – 40 years −0.16 (−0.56-0.24) −15 0.43 0.04 (−0.39-0.46) 4.1 0.86 −0.09 (−0.38-0.21) −8.6 0.57
> 40 years −0.21 (−0.62-0.21) −19 0.33 −0.47 (−0.93- -0.01) −37 0.04 −0.37 (−0.68- -0.05) −31 0.02
Study          
HB NA NA NA NA NA NA Reference Reference  
Infant leukemia NA NA NA NA NA NA 0.05 (−0.15-0.26) 5.1 0.63
Case control status         
Control Reference Reference   Reference Reference   Reference Reference  
Case −0.13 (−0.41-0.16) −12 0.38 0.41 (0.09-0.72) 51 0.01 0.14 (−0.08-0.36) 15 0.21
Maternal race          
White Reference Reference   Reference Reference   Reference Reference  
Other 0.10 (−0.23-0.44) 11 0.54 0.13 (−0.27-0.53) 14 0.53 0.13 (−0.14-0.39) 14 0.34
Season of DNA collection         
Spring Reference Reference   Reference Reference   Reference Reference  
Summer 0 (−0.37-0.37) 0 1.00 0.30 (−0.12-0.73) 35 0.16 0.18 (−0.10-0.46) 20 0.20
Fall −0.19 (−0.57-0.20) −18 0.35 0.82 (0.43-1.21) 127 <0.0001 0.39 (0.11-0.66) 48 0.007
Winter 0.25 (−0.15-0.65) 28 0.22 0.46 (0.04-0.87) 58 0.03 0.35 (0.06-0.64) 42 0.02
  1. a Models were adjusted for all other variables in table.
  2. b Percent change in DNA yield relative to referent.