Figure 3

Power for permutation-based gene test as a function of causal SNP’s location relative to correlated region and size of LD block. For a constant effect size, size of the LD block in which the causal SNP is (or is not) located is related to the power for detection. The black, solid power curve refers to the permutation-based gene test when the causal SNP is in the LD block, and the blue, dashed power curve refers to the test when the causal SNP is not in the LD block.