Figure 2From: Genome-wide mRNA sequencing of a single canine cerebellar cortical degeneration case leads to the identification of a disease associated SPTBN2 mutationSubacute loss of Purkinje cells (PC) is documented by so-called “empty baskets” (EB) that have been visualised by Bielschowsky´s impregnation technique. The baskets (white arrows) synapse to the PC perikarya and in order to inhibit PC activity. ML: molecular layer; GL: granule cell layer; scale bar: 40 μm.Back to article page