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Table 1 Association results for chromosome 5q31 SNPs with LDL-cholesterol traits in the combined GENECARD and CATHGEN cohorts.

From: Fine mapping of a linkage peak with integration of lipid traits identifies novel coronary artery disease genes on chromosome 5

SNP

Gene

Physical Location (bp)

P-value

rs10074645

PRELID2

144965385

0.001

rs1895172

ADAMTS19

128874733

0.002

rs6893183

PRELID2

145018484

0.005

rs1865009

PRELID2

144989633

0.01

rs1460038

intergenic

122077475

0.01

rs32652

TNFAIP8

118705545

0.01

rs11957633

SIL1

138364394

0.01

rs17103583

PRELID2

145044493

0.01

rs17600115

SPOCK1

136420952

0.01

rs7727137

intergenic

122081840

0.01

rs1460039

RP11-166A12.1

122051006

0.01

rs2125443

PPP2R2B

146229428

0.01

rs4921307

ATP10B

160026777

0.02

rs1558095

intergenic

135429640

0.02

rs1558095

intergenic

135429640

0.02

rs728937

intergenic

146485682

0.02

rs7721110

SIL1

138482506

0.02

rs17164449

CTC-228N24.3

127342272

0.02

rs2304052

SPARC

151054227

0.03

rs246869

FAM71B

156584384

0.03

rs44156

intergenic

157625206

0.03

rs6596460

SIL1

138414180

0.03

rs876600

SLC27A6

128235848

0.03

rs6595178

DMXL1

118532034

0.03

rs6863332

intergenic

159234840

0.03

rs962271

ATP10B

160054549

0.03

rs418210

GABRG2

161580983

0.03

rs889010

TRPC7

135572910

0.03

rs367153

ITK

156610846

0.04

rs383915

SLC36A2

150695724

0.04

rs35525

MEGF10

126699347

0.04

rs10875552

PPARGC1B

149189489

0.04

rs12374480

intergenic

154001174

0.04

rs2240793

SLC6A7

149583300

0.04

rs4913054

SH3RF2

145339561

0.04

rs880770

PPARGC1B

149154835

0.04

rs1036199

HAVCR2

156531736

0.04

rs13182800

NR3C1

142801480

0.04

rs12188371

intergenic

117764534

0.04

rs6556615

SGCD

155859368

0.04

rs938537

intergenic

160458036

0.04

rs4244032

NR3C1

142794725

0.04

rs1350375

intergenic

161358888

0.05

rs6595416

SNX24

122268004

0.05

rs1800449

SRFBP1

121413208

0.05

rs2950952

SPOCK1

136654594

0.05

rs193730

intergenic

141154583

0.05

rs162486

intergenic

123073478

0.05

rs586115

FBN2

127662875

0.05

rs17717527

EBF1

158466283

0.05

rs1465689

ARSI

149685855

0.05

  1. The 51 SNPs with p-values ≤0.05 using Fisher's method for combining results from CATHGEN and GENECARD are presented.. Results for the four candidate genes (PPP2R2B, EBF1, SPOCK1, and PRELID2) are in bold.