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Table 1 Parameters for Simulation under Alternative Hypothesis

From: A powerful hybrid approach to select top single-nucleotide polymorphisms for genome-wide association study

 

Disease Locus 1

Marker 1

Disease Locus 2

Marker 2

 

(D1)

(M1)

(D2)

(M2)

OR

1.8

 

1.5

 

MAF

10%

10%

40%

40%

  1. OR = odds ratio, MAF = minor allele frequency, LD = linkage disequilibrium.
  2. The LD between the disease loci and the corresponding marker loci is 0.8, and the two disease loci are in linkage equilibrium.
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BMC Genomic Data

ISSN: 2730-6844

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