Figure 3From: A major QTL controls susceptibility to spinal curvature in the curveback guppyIdentification of susceptibility locus. Curve predisposition is recessive. Therefore, curved individuals that were not homozygous for the allele from the curved parent (i.e. recombinants) at a given marker exclude that marker from the QTL region. By genotyping curved individuals at each marker within the QTL defined in Figure 2, we were able to identify a region in which all curved individuals are homozygous for the curved allele. Marker 0289 (at 13 cM) defines locus 1 and accounts for 100% of curve susceptibility. Flanking markers 0635 and 0381 at 9.35 and 14.5 cM are heterozygous in one or more curved individuals and so delimit the QTL region. *For the marker at 14.5 cM only the curved individuals who are heterozygous at 15.96 or 9.35 were genotyped.Back to article page