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Table 6 Simultaneous two-locus search with incorporation of "Maximum number of drinks in a 24 hour period" -- nonparametric approach

From: Incorporation of covariates in simultaneous localization of two linked loci using affected relative pairs

 

ESTIMATE

(S.E.) or [95% CI]

 

Ï„1 (cM)

Ï„2 (cM)

C1

C2

λ 1

λ 2

Using one ARP only:

      

   Full siblings

58.97

124.42

0.084

0.16

1.20

1.45

    

[-0.004,0.27]

[0.94,1.71]

[0.99,2.21]

 

(3.37)

(4.99)

[-0.03,0.21]

   

   Avuncular pairs

60.66

123.46

0.018

0.048

1.07

1.21

    

[-0.081,0.19]

[0.64,1.58]

[0.77,1.69]

 

(0.24)

(4.84)

[-0.11,0.11]

   

Using both ARPs:

      

   Full siblings

  

0.083

0.16

1.20

1.45

   

[-0.005,0.22]

[0.011,0.26]

[0.99,1.79]

[1.02,2.09]

   Avuncular pairs

  

0.017

0.051

1.07

1.23

   

[-0.11,0.12]

[-0.052,0.18]

[0.63,1.62]

[0.81,2.10]

   Common τ

60.81

124.24

    
 

(0.16)

(2.29)

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