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Table 5 Simultaneous two-locus search with incorporation of "Maximum number of drinks in a 24 hour period" - parametric approach

From: Incorporation of covariates in simultaneous localization of two linked loci using affected relative pairs

 

ESTIMATE

(S.E.) or [95% CI]

 

Ï„1 (cM)

Ï„2 (cM)

C1

C2

λ 1

λ 2

Using one ARP only:

      

   Full siblings

58.95

126.55

0.16

0.24

1.45

1.90

 

(2.42)

(3.43)

[-0.01,0.32]

[0.07,0.43]

[0.91,2.76]

[1.11,7.18]

   Avuncular pairs

75.14

123.55

-0.07

0.04

0.76

1.17

 

(0.72)

(5.85)

[-0.15,0.21]

[-0.15,0.24]

[0.54,2.40]

[0.65,2.07]

Using both ARPs:

      

   Full siblings

  

0.16

0.23

1.46

1.82

   

[-0.08,0.32]

[0.02,0.43]

[0.86,2.70]

[1.03,6.68]

   Avuncular pairs

  

0.005

0.04

1.02

1.16

   

[-0.15,0.20]

[-0.21,0.23]

[0.54,2.38]

[0.40,2.65]

   Common τ

58.53

127.41

    
 

(1.47)

(1.99)

    
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BMC Genomic Data

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