Skip to main content

Table 2 Inter-method variation in TP53 genotyping

From: Validation of dot blot hybridization and denaturing high performance liquid chromatography as reliable methods for TP53 codon 72 genotyping in molecular epidemiologic studies

Typing method

Frequency of joint distribution (%)

Weighted Kappa Coefficient

 

Agreement

Disagreement

 

DHPLC × Dot Blot

919 (95.5)

43 (4.5)

0.92

DHPLC × Bsa JI

887 (92.2)

75 (7.8)

0.88

DHPLC × Bst UI

860 (89.4)

102 (10.6)

0.83

Dot Blot × Bsa JI

895 (93.0)

67 (7.0)

0.90

Dot Blot × Bst UI

864 (89.8)

98 (10.2)

0.85

Bsa JI × Bst UI

869 (90.3)

93 (9.7)

0.85